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Craig Mello, Ph.D.
Academic Role: Professor
Faculty Appointment(s) In:
Program in Molecular Medicine
Other Affiliation(s):
Cancer Center
Cell Biology
Cell Dynamics Group
Center for AIDS Research
Interdisciplinary Graduate Program
Recent Publications
Nakamura, K., Kim, S., Ishidate, T., Bei, Y., Pang, K-M, Shirayama, M., Trzepacz, C., Brownell, D.R., Mello, C.C. (2005) Wnt signaling drives WRM-1/ß-catenin asymmetries in early C. elegans embryos. Genes Dev. 2005 Aug 1;19(15);1749-54.
Wang, D., Kennedy, S., Conte Jr., D., Kim, J.K., Gabel, H.W., Kamath, R., Mello, C.C., Ruvkun, G., (2005). Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants. Nature July 28; 436(7050) 593-7.
Shirayama, M., Soto, M.C., Ishidate, T., Kim, S., Nakamura, K., Bei, Y., van den Heuvel, S., Mello, C.C. (2006) The Conserved Kinases CDK-1, GSK-3, KIN-19, and MBK-2 Promote OMA-1 Destruction to Regulate the Oocyte-to-Embryo Transition in C. elegans. Current Biology Jan 10;16(1):47-55
Duchaine, T.F., Wohlschlegel, J.A., Kennedy, S., Bei, Y., Conte, D., Pang, K-M., Brownell, D.R., Harding, S., Mitani, S., Ruvkun, G., Yates, J.R. Mello, C.C. (2006) Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Cell Jan 27;124(2):343-54.
Yigit, Y., Batista, P.J., Bei, Y., Pang, K-M., Chen, C-C.G., Tolia, N.H., Joshua-Tor, L., Mitani, S., Simard, M.J., Mello, C.C. (2006) Analysis of the C. elegans Argonaute family reveals that distinct Argonautes Act Sequentially During RNAi. Cell 127 November 12, 747-757.
Mello, C.C. (2007) Return to the RNAi World: Rethinking Gene Expression and Evolution. (Nobel Lecture) Angewandte Chemie Int. Ed. 2007, 46, 6985-6994.
Office: Biotech Two, Suite 219
Phone: 508-856-1602
E-mail: Craig.Mello@umassmed.edu
Keywords:
RNA Interference (RNAi),
Signal Transduction,
Gene Expression,
Developmental Biology
Postdoctoral Position Available
A postdoctoral position is available to study in this laboratory.
Contact Dr. Mello for additional details.
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