Section: Figures

Mary Lee, M.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Cell Biology
   Pediatrics

Figure 1. Mullerian Inhibiting Substance (MIS) is a negative regulator of progenitor Leydig cell proliferation and differentation and an inhibitor of adult Leydig cell androgen biosynthesis.  

Figure 2. TUNEL staining of representative light micrographs of 4-µm-thick testicular sections from MIS and control-treated rats on Day 15 after EDS treatment. A) Control rat. B and C) MIS-treated rats. Most of the TUNEL-positive nuclei are located within the seminferous tubules and correspond to germ cells. Arrow: interstitial cell with TUNEL-positive nucleus. Scale bar = (A and B) 100 µm and (C) 25 µm. (Salva A, et al. Biology of Reproduction 2004;70:600-607)

Phone: 508-856-4280
E-mail: Mary.Lee@umassmemorial.org
Keywords: Reproductive Endocrinology, Transgenic Mice, Cell Biology, Male Reproductive Biology, Testis Development

More on Mary Lee's Research Research | Figures | Publications | Rotations | Biography View All Sections on One Page