David Lapointe, Ph.D.

Other Affiliation(s):
   Cell Biology
   Center for AIDS Research

Bioinformatics

Recent Publications

Jang T, Savarese T, Low HP, Kim S, Vogel H, Lapointe D, Duong T, Litofsky NS, Weimann JM, Ross AH, Recht L. Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea. Am J Pathol. 2006 May;168(5):1676-85

Warke RV, Xhaja K, Martin KJ, Fournier MF, Shaw SK, Brizuela N, de Bosch N, Lapointe D, Ennis FA, Rothman AL, Bosch I. Dengue virus induces novel changes in gene expression of human umbilical vein endothelial cells. J Virol. 2003 Nov;77(21):11822-32.

Balint E, Lapointe D, Drissi H, van der Meijden C, Young DW, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation. J Cell Biochem. 2003 May 15;89(2):401-26.

van der Meijden CM, Lapointe DS, Luong MX, Peric-Hupkes D, Cho B, Stein JL, van Wijnen AJ, Stein GS. Gene profiling of cell cycle progression through S-phase reveals sequential expression of genes required for DNA replication and nucleosome assembly. Cancer Res. 2002 Jun 1;62(11):3233-43.

Selected Prior Publications

Lapointe DS, Olson MS.Compartmental analysis of ⁴⁵Ca²⁺ efflux in perfused rat liver: effects of hormonal stimulation. Cell Calcium. 1991 Nov;12(10):743-53.

Lapointe DS, Olson MS.Alteration of hepatic tissue spaces by platelet-activating factor and phenylephrine. Hepatology. 1989 Feb;9(2):278-84

Lapointe DS, Hanahan DJ, Olson MS.Mobilization of hepatic calcium pools by platelet activating factor. Biochemistry. 1987 Mar 24;26(6):1568-74.

Savageau MA, Lapointe DS. Optimization of kinetic proofreading: a general method for derivation of the constraint relations and an exploration of a specific case. J Theor Biol. 1981 Nov 7;93(1):157-77.

Office: SB-713
Phone: 508-856-5141
E-mail: David.Lapointe@umassmed.edu
Keywords: Proteomics, Bioinformatics, Gene Expression, Genomics, Systems Biology

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