Section: Publications

Harvey Florman, Ph.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Cell Biology
   Physiology

Other Affiliation(s):
   Biochemistry and Molecular Pharmacology
   Interdisciplinary Graduate Program

Selected Publications

Arnoult, C., Kazam, I.G., Visconti, P., Villaz, M., Kopf, G.S., and Florman, H.M.  (1999) Control of the low voltage-activated calcium channel of mouse sperm by egg ZP3 and by membrane hyperpolarization during capacitation.  Proc. Natl. Acad. Sci. USA (USA) 96, 6757-6762.PMID: 10359785

O’Toole, C.M.B., Arnoult, C., Darszon, A., Steinhardt, R.H., and Florman, H.M.  (2000) Ca²⁺ entry through store-operated channels in mouse sperm is initiated by egg ZP3 and drives the acrosome reaction Mol. Biol. Cell 11, 1571-1584. PMID: 10793136 http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=14868

Jungnickel, M.K., Marrero, H., Birnbaumer, L., Lemos, J.R., and Florman, H.M.  (2001) Trp2 regulates the Ca²⁺ entry into mouse sperm triggered by egg ZP3.  Nature Cell Biology 3, 499-502. PMID: 12042831
http://www.nature.com/ncb/journal/v3/n5/pdf/ncb0501_499.pdf

Evans, J.P., and Florman, H.M. (2002)  The state of the union: the cell biology of fertilization.  Nature Medicine 8, S57-S63.

Jungnickel, M.K., Sutton, K.A., and Florman, H.M. (2003) In the beginning: lessons from fertilization in mice and worms.  Cell 114, 401-404. PMID: 12941269

Sutton, K.A., Jungnickel, M.K., Wang, Y., Cullen, K., Lambert, S., and Florman, H.M.   (2004) Enkurin is      a novel TRPC channel and calmodulin interacting protein from sperm. Dev. Biol. 274, 426-435. PMID: 15385169

Galantino-Homer, H.L., Florman, H.M., Storey, B.T., Dorinski, I., and Kopf, G.S. (2004)  Bovine sperm capacitation: assessment of phosphodiesterase activity and intracellular alkalinization on capacitation-associated protein tyrosine phosphorylation.  Mol. Reprod. Dev. 67, 487-500.  PMID: 14991741

Florman, H.M., and Ducibella, T. (2006)  Fertilization in mammals.  In: The Physiology of Reproduction, 3^rd Edition (J. Neill, ed.) Elsevier Press. San Diego: pp. 55-112.

Sutton, K.A., Jungnickel, M.K., Ward, C.J., Harris, P.C., and Florman, H.M. (2006) Functional characterization of PKDREJ, a male germ cell-restricted polycystin.  J. Cell. Physio. 209, 493-500.  PMID: 16883570
http://www3.interscience.wiley.com/cgi-bin/fulltext/112738197/PDFSTART

Jungnickel, M.K., Sutton, K.A., Wang, Y., and Florman, H.M. (2007) Phosphoinositide-dependent pathways in mouse sperm are regulated by egg ZP3 and drive the acrosome reaction.  Dev. Biol. 304, 116-126. PMID: 17258189
http://www.pubmedcentral.nih.gov/picrender.fcgi?tool=pmcentrez&artid=1892180&blobtype=pdf

Sutton, K.A., Jungnickel, M.K., and Florman, H.M. (2008) A polycystin-1 controls post-copulatory reproductive selection in mice. Proc. Natl. Acad. Sci. USA 105, 8661-8666. PMID: 18562295
http://www.pnas.org/cgi/content/full/105/25/8661

Office: S7-304
Phone: 508-856-1675
Fax: 856-5612
E-mail: Harvey.Florman@umassmed.edu
Keywords: Signal Transduction, Male Reproductive Biology, Electrophysiology, Ion Channels, Imaging and Microscopy

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