Section: Publications

Postdoctoral Position Available

Roger Craig, Ph.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Cell Biology

Other Affiliation(s):
   Cell Dynamics Group

Recent Publications

Woodhead, J.L., Zhao, F.-Q., Craig, R., Egelman, E.H., Alamo, L., and Padron, R. (2005).  Atomic model of a myosin filament in the relaxed state.  Nature 436, 1195-1199.

Pirani, A., Xu, C., Hatch, V., Craig, R., Tobacman, L.S., and Lehman, W. (2005).  Single particle analysis of relaxed and activated muscle thin filaments.  J. Mol. Biol. 346, 761-772.

Zoghbi M.E., Woodhead J.L., Craig R., and Padrón R.  (2004).  Helical order in tarantula thick filaments requires the Aclosed@ conformation of the myosin head.  J. Mol. Biol. 342, 1223-1236.

Zhao, F.-Q. and Craig, R. (2003).  Ca²⁺ causes release of myosin heads from the thick filament surface on the milliseconds time scale.  J. Mol. Biol.  327, 145-158.

Zhao, F.-Q. and Craig, R.  (2003).  Capturing time-resolved changes in molecular structure by negative staining.  J. Struct. Biol.  141, 43-52.

Hatch, V., Zhi, G., Smith, L., Stull, J.T., Craig, R., and Lehman, W.  (2001).  Myosin light chain kinase binding to a unique site on F-actin revealed by three-dimensional image reconstruction.  J. Cell Biol.  154, 611-617.

Stafford, W.F., Jacobsen, M.P., Woodhead, J., Craig, R., O=Neall-Hennessey, E., and Szent-Györgyi, A.G. (2001).  Calcium-dependent structural changes in scallop heavy meromyosin.  J. Mol. Biol.  307, 137-147.

Xu, C., Craig, R., Tobacman, L., Horowitz, R. and Lehman, W. (1999).  Tropomyosin positions in regulated thin filaments revealed by cryoelectron microscopy.  Biophys. J. 77, 985-992.

Vibert, P., Craig, R., and Lehman, W. (1997). Steric-model for activation of muscle thin filaments. J. Mol. Biol. 266, 8-14.

Hodgkinson, J.L., El-Mezgueldi, M., Craig, R., Vibert, P., Marston, S.B., and Lehman, W. (1997).  3D Image reconstruction of reconstituted smooth muscle thin filaments containing calponin.  J. Mol. Biol.   273, 150-159.

Lehman, W., Vibert, P. and Craig, R. (1997).  Visualization of caldesmon in three-dimensional reconstructions of smooth muscle thin filaments.  J. Mol. Biol.  274, 310-317.

Xu, J.-Q., Harder, B., Uman, P. and Craig, R. (1996).  Myosin filament structure in vertebrate smooth muscle.  J. Cell Biol. 134, 53-66.

Lehman, W., Craig, R. and Vibert, P.  (1994).  Ca²⁺-induced tropomyosin movement in Limulus thin-filaments revealed by three-dimensional reconstruction.  Nature 368, 65-67.

Office: S7 210, LAB: S7-209-213
Phone: 508-856-2474
E-mail: Roger.Craig@umassmed.edu
Keywords: Cellular Architecture, Cell Motility, Biophysics, Structural Biology, Imaging and Microscopy

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Postdoctoral Position Available A postdoctoral position is available to study in this laboratory. Contact Dr. Craig for additional details.