Section: Publications

Postdoctoral Position Available

Zheng-Zheng Bao, Ph.D.

Academic Role: Associate Professor

Faculty Appointment(s) In:
   Cell Biology
   Endocrinology
   Medicine

Other Affiliation(s):
   Cell Dynamics Group
   Center for AIDS Research
   Interdisciplinary Graduate Program
   Program in Neuroscience

Representative Publications

Kopak, A., Jiang, J., Guo, D., Standley, C., Bellve, K., Forgarty, K., Bao, Z. Z. (2009).  Negative guidance factor-induced macropinocytosis in the growth cone plays a critical role in repulsive axon turning.  J. Neurosci.  29:10488-98.

Bao, Z. Z. (2008).  Intraretinal projection of retinal ganglion cell axon as a model system for studying axon navigation.  Brain Res. 1192:165-177.

Chau, M., Tuft, R., Fogarty, K., Bao, Z. Z. (2006).  Notch signaling plays a key role in cardiac differentiation.  Mech. Dev.  123:626-640.

Bao, Z. Z. and Jin, Z. (2006).  Sema3D and Sema7A have distinct expression patterns in chick embryonic development.  Dev. Dyn.  235:2282-2289.

Jin, Z., Chau, M., Bao, Z. Z. (2006).  Sema3D, Sema3F, and Sema5A are expressed in overlapping distinct patterns in chick embryonic heart.  Dev. Dyn. 235:163-169.

Kolpak, A., Zhang, J., Bao, Z. Z. (2005). Sonic hedgehog has a dual effect on the growth of retinal ganglion axons depending on its concentration.  J. Neurosci. 25(13): 3432-41.  With accompanying Editor’s highlight.

Zhang, J., Jin, Z., Bao, Z. Z. (2004). Disruption of gradient expression of Zic3 resulted in aberrant projection of the retinal ganglion axons to the optic disc.  Development,131: 1553-1562. 

Jin, Z., Zhang, J., Klar, A., Chédotal, A., Rao, Y., Cepko, C., Bao, Z. Z. (2003). Irx4-mediated regulation of Slit1 expression contributes to the definition of early axonal paths inside the retina.  Development, 130: 1037-1048.

Bruneau, B. G., Bao, Z. Z., Fatkin, D., Georgakopoulos, D., Kass, D. A., Mudd, J. O., Schoen, F. J., de Bold, A. J., Cepko,, C. L., Seidman, J. G., Seidman, C. E. (2001). Irx4 -targeted mice reveal a novel pathway for cardiomyopathy and ventricle-specific gene expression. Mol. Cell Biol. 21: 1730-1736.

Wang, G. F., Nikovits, W., Bao, Z. Z., Stockdale, F. E. (2001).  Irx4 Forms an Inhibitory Complex with the Vitamin D and Retinoic X Receptor to Regulate Chamber-Specific Slow MyHC3 Expression. J. Biol. Chem. 276: 28835-28841.

Bruneau, B. G., Bao, Z. Z., Tanaka, M., Schott, J.-J., Izumo, S., Cepko, C. L., Seidman, C., Seidman, J. G. (2000) Cardiac expression of the ventricle-specific homeobox gene Irx4 is regulated by Nkx2-5- and Hand2-dependent pathways.  Dev. Biol. 217: 266-277.

Furukawa, T., Mukherjee, S., Bao, Z. Z., Morrow, E. and Cepko, C. L. (2000). Rax , Hes1, and Notch1 promote the formation of Müller glia by postnatal retinal progenitor cells.  Neuron. 26: 383-394

Bao, Z. Z., Bruneau, B. G., Seidman, J. G., Seidman, C. E., and Cepko, C. L.. (1999). Regulation of chamber-specific gene expression in the developing heart by Irx4. Science, 283, 1161-1164.

Office: LRB #221
Phone: (508) 856-3202
E-mail: Zheng-Zheng.Bao@umassmed.edu
Keywords: Neurobiology, Genetics, Signal Transduction, Cell Biology, Developmental Biology

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Postdoctoral Position Available A postdoctoral position is available to study in this laboratory. Contact Dr. Bao for additional details.