Cell Biology Researchers Receive Six Million Dollar Grant from NCI

NCI research groupSix Department of Cell Biology faculty members; Gary Stein, Anthony Imbalzano, Janet Stein, Jane Lian, Andre van Wijnen and Jeffrey Nickerson are part of a multidisciplinary team of researchers in the Department of Cell Biology and the UMass Memorial Cancer Center of Excellence that have been awarded a $6 million, five-year grant by the National Cancer Institute (NCI) to investigate the organization of genes and other genomic elements in cancer cells that control whether tumor cells grow rapidly and spread to other organs in the body, a process known as metastasis.

Led by Gary Stein, PhD, the Gerald L. Haidak, MD, and Zelda S. Haidak Professor of Cell Biology, co-director of the UMass Memorial Cancer Center of Excellence and chair and professor of cell biology,, the team will use cutting-edge genomic sequencing strategies and high-resolution imaging to build on their earlier discoveries related to changes in the architectural organization of genes and other factors that control tumor cell proliferation and metastasis. They are now focusing on translating these discoveries into strategies for early-stage diagnosis of breast cancer, prostate cancer and leukemia, as well as to the treatment of breast and prostate tumors that metastasize to bone.

Read full article in UMMS News.