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Eric Baehrecke, Ph.D.
Academic Role: Professor
Faculty Appointment(s) In:
Cancer Biology
Other Affiliation(s):
Graduate School of Biomedical Sciences
Select Publications
Dutta S., and Baehrecke E.H. (2008) Warts is required for PI3K-regulated growth arrest, autophagy and autophagic cell death in Drosophila. Curr. Biol. 18, 1466-1475.
Juhász G., Hill J.H., Yang Y., Sass M., Baehrecke E.H., Backer J.M. and Neufeld T.P. (2008) The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila. J. Cell Biol. 181, 655-666.
Berry D.L. and Baehrecke E.H. (2007) Growth arrest and autophagy are required for programmed salivary gland cell degradation in Drosophila. Cell 131, 1137-1148.
Pandey U.B., Nie Z.P., Batlevi Y., McCray B.A., Ritson G.P., Schwartz S.L., DiProspero N., Knight M., Schuldiner O., Padmanabhan R., Hild, M., Berry D.L., Garza D., Hubbert C.C., Yao T.-P., Baehrecke E.H. and Taylor J.P. (2007) HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the ubiquitin-proteasome system. Nature 447, 860-864.
Martin D.N., Balgley B., Dutta S., Chen J., Cranford J., Kantartzis S., Rudnick P., DeVoe D.L., Lee C. and Baehrecke E.H. (2007) Proteomic analysis of steroid-triggered autophagic programmed cell death in Drosophila. Cell Death Diff. 14, 916-923.
Muro I., Berry D.L., Huh J.R., Chen C.H., Seoul J.H., Yoo S.J., Guo M., Baehrecke E.H. and Hay B.A. (2006) The Drosophila caspase Drice is important for many apoptotic cell deaths as well as a nonapoptotic process, spermatid individualization. Development 133, 3305-3315.
Yu L., Wan F., Dutta S., Welsh S., Liu Z., Freundt E., Baehrecke E.H. and Lenardo M.J. (2006) Autophagic programmed cell death by selective catalase degradation. Proc. Natl. Acad. Sci. USA 103, 4952-4957.
Baehrecke E.H. (2005) Autophagy: dual roles in life and death? Nature Reviews Mol. Cell Biol. 6, 505-510.
Yu L., Alva A., Su H., Dutt P., Freundt E., Welsh S., Baehrecke E.H. and Lenardo M.J. (2004) Regulation of an ATG7-Beclin 1 program of autophagic cell death by caspase-8. Science 304, 1500-1502.
Baehrecke E.H., Dang N., Barbaria K. and Shneiderman B. (2004) Visualization and analysis of microarray and gene ontology data with treemaps. BMC Bioinformatics 5, 84.
Alva A., Gultekin H., and Baehrecke E.H. (2004) Autophagy in human tumors: cell survival or death? Cell Death Diff. 11, 1046-1048.
Martin D. and Baehrecke E.H. (2004) Caspases function in autophagic programmed cell death in Drosophila. Development 131, 275-284.
Lee C.-Y., Clough E., Yellon P., Teslovich T., Stephan D. and Baehrecke E.H. (2003) Genome-wide analyses of steroid- and radiation-triggered programmed cell death in Drosophila. Curr. Biol. 13, 350-357.
Baehrecke E.H. (2002) How death shapes life during development. Nature Reviews Mol. Cell Biol. 3, 779-787.
Lee C.-Y., Simon C.R., Woodard C.T., and Baehrecke E.H. (2002) Genetic mechanism for the stage- and tissue-specific regulation of steroid-triggered programmed cell death in Drosophila. Dev. Biol. 252, 138-148.
Lee C.-Y., Cooksey B.A.K. and Baehrecke E.H. (2002) Steroid regulation of midgut cell death during Drosophila development. Dev. Biol. 250, 101-111.
Lee C.-Y. and Baehrecke E.H. (2001) Steroid regulation of autophagic programmed cell death during development. Development 128, 1443-1455.
Lee C.-Y., Wendel D.P., Reid P., Lam, G., Thummel C.S. and Baehrecke E.H. (2000) E93 directs steroid-triggered programmed cell death in Drosophila. Molecular Cell 6, 433-443.
Office: LRB 423
Phone: 508-856-6733
E-mail: Eric.Baehrecke@umassmed.edu
Keywords:
Cell Death
Postdoctoral Position Available
Postdoctoral positions are available for this lab. Please contact Eric Baehrecke directly, 508-856-6733 or via email, Eric.Baehrecke@umassmed.edu
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