Section: Rotations

Postdoctoral Position Available

Haley Melikian, Ph.D.

Academic Role: Associate Professor

Faculty Appointment(s) In:
   Psychiatry

Joint Faculty In:
   Biochemistry and Molecular Pharmacology

Other Affiliation(s):
   Brudnick Neuropsychiatric Research Institute
   Interdisciplinary Graduate Program
   Program in Neuroscience

Potential Rotation Projects

1. This project is to determine the intrinsic motif that targets transporters for internalization from the cell surface. Students will generate transporter point mutants lacking candidate internalization signals and subsequently assess transporter function and trafficking. Students will gain experience with molecular biology techniques, mammalian cell culture, pharmacological assays and cellular trafficking studies.



2. This project is to determine how different transporter isoforms differ in their ability to traffic and be regulated. Students will isolate mRNA from cell lines, perform RT-PCR to identify transporter isoform expression and assess how co-expression of transporter isoforms impacts transporter downregulation. Students will gain experience with molecular biology techniques, mammalian cell culture and pharmacological assays.

Office: BNRI
Phone: 508 856-4045
E-mail: Haley.Melikian@umassmed.edu
Keywords: Intracellular Trafficking, Pharmacology, Addiction, Membrane Transport, Neurobiology

More on Haley Melikian's Research Research | Publications | Rotations | Biography View All Sections on One Page

Postdoctoral Position Available Postdoctoral positions (PhD, MD, and/or DVM) are available for outstanding candidates at the new Irving S. and Betty Brudnick Neuropsychiatric Research Institute in the Department of Psychiatry. The Institute provides a translational research environment in which to study: Molecular analyses of cocaine- and antidepressant-sensitive monoamine transporters Interested applicants should mail or fax a curriculum vitae and three letters of reference to the attention of: Haley E. Melikian, PhD Irving S. and Betty Brudnick Neuropsychiatric Research Institute Department of Psychiatry University of Massachusetts Medical School Room 107 303 Belmont Street Worcester, MA 01604 The University of Massachusetts Medical School is an Equal Employment Opportunity/Affirmative Action Institution.