Section: Rotations

Celia Schiffer, Ph.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Biochemistry and Molecular Pharmacology

Other Affiliation(s):
   Center for AIDS Research
   Interdisciplinary Graduate Program

Possible Rotation Projects

1. Site directed mutagenesis and enzyme kinetics of HIV protease to determine the role of strongly conserved residues.
2. Refinement of crystal structures of HIV protease in complex with substrates or inhibitors
3. Analysis of molecular dynamics trajectories of HIV protease. Analysis of the water, peptide and protein structure.

Office: Research 923, Lab 970 L&M
Phone: 508-856-8008
E-mail: Celia.Schiffer@umassmed.edu
Keywords: Biophysics, Drug Design, Structural Biology, Infectious Disease, HIV/AIDS

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