Charles Sagerstrom, Ph.D.
Academic Role: Associate Professor
Faculty Appointment(s) In:
Biochemistry and Molecular Pharmacology
Other Affiliation(s):
Interdisciplinary Graduate Program
Recent Publications
C.G. Sagerström, Y. Grinblat and H. Sive. (1996). Anteroposterior patterning in the zebrafish, Danio rerio: an explant assay reveals inductive and suppressive cell interactions. Development.122: 1873-1883.
C.G. Sagerström and H.L. Sive. (1996). RNA blot analysis. In A laboratory guide toRNA: Isolation, Analysis and Synthesis. Ed. P. Krieg. Wiley-Liss, Inc. pp 83-103.
C.G. Sagerström, B.I. Sun, and H.L. Sive. (1997). Subtractive hybridization: Past present and future. Ann. Rev. Biochem. 66:751-783.
C.G. Sagerström. (1997) Slippery slopes: Understanding gradients and asymmetries in development. Trends in Cell Biology 7:463-465.
Y. Grinblat, M. Lane, C.G. Sagerström and H. Sive. (1998). Analysis of zebrafish development using explant culture assays. Meth. Cell Biol. 59:128-155.
N. Vlachakis, D. Ellstrom and C.G. Sagerström. (2000). A novel Pbx family member expressed during early zebrafish embryogenesis forms trimeric complexes with Meis3 and Hoxb1b. Developmental Dynamics 217:109-119.
C.G. Sagerström, B. Kao, M. Lane and H.L. Sive. (2001). Isolation and characterization of posteriorly restricted genes in the zebrafish gastrula. Developmental Dynamics 220:402-408.
N. Vlachakis, S-K. Choe and C. G. Sagerström. (2001). Meis3 synergizes with Pbx4 and Hoxb1b in promoting hindbrain fates in the zebrafish. Development 128:1299-1312.
S.-K. Choe, N. Vlachakis and C. G. Sagerström. (2002). Meis family proteins are required for hindbrain development in the zebrafish. Development 129:585-595.
L. Etheridge, P. diIorio and C. G Sagerström (2002). A zebrafish unc-45 related gene expressed during muscle development. Developmental Dynamics 224:457-460.
M. E. Lane , A. P. Runko, N. M. Roy, and C. G. Sagerström. (2002). Dynamic expression and regulation by Fgf8 and Pou2 of the zebrafish LIM-only gene lmo4. Mechanisms of Development 119: S185-189.
K. M. Astrofsky, R. A. Bullis and C. G. Sagerström (2002). Biology and management of the zebrafish. In Laboratory Animal Medicine. 2nd edition. Ed. J. Fox, L. Anderson, F. Loew, F. Quimby, pp. 861-883. Academic
A. P. Runko and C. G. Sagerström. (2003). Nlz belongs to a family of zinc-finger containing repressors and controls segmental gene expression in the zebrafish hindbrain. Developmental Biology 262:254-267.
N. M. Roy and C. G. Sagerström (2004). An early Fgf-signal required for gene expression in the zebrafish hindbrain primordium. Developmental Brain Research. 148: 27-42.
A. P. Runko and C. G. Sagerström (2004). Isolation of nlz2 and characterization of essential domains in Nlz-family proteins. Journal of Biological Chemistry 279: 11917-11925.
S. –K. Choe and C. G. Sagerström. (2004). Paralog group 1 hox genes regulate rhombomere 5/6-expression of vhnf1, a repressor of rostral hindbrain fates, in a meis-dependent manner. Developmental Biology 271:350-361.
M. Nakamura, A. P. Runko and C. G. Sagerström. (2004). A novel zinc-finger subfamily regulating embryogenesis. Journal of Cellular Biochemistry. 93:887-895
C. G. Sagerström. (2004). pbX marks the spot. Developmental Cell 6: 737-738
C. G. Sagerström, L. S. Gammill, R. Veale and H. Sive. (2005). Specification of the enveloping layer and lack of autoneuralization in zebrafish embryonic explants. Developmental Dynamics 232: 85-97.
S. –K. Choe and C. G. Sagerström. (2005). Variable meis-dependence among paralog group-1 hox genes. Biochemical and Biophysical Research Communications. 331:1384-1391.
Office: LRB-815, Lab 870 D-F
Phone: 508-856-8006
E-mail: Charles.Sagerstrom@umassmed.edu
Keywords:
Neurobiology,
Gene Expression,
Developmental Biology
Postdoctoral Position Available
A postdoctoral position is available to study in this laboratory.
Contact Dr. Sagerström for additional details.
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