Publications

W.E. Royer, Jr., K. Strand, M. vanHeel, W.A. Hendrickson (2000) “Structural hierarchy in erythrocruorin, the giant respiratory assemblage of annelids” Proc. Natl. Acad. Sci. 97, 7107-7111

W.E. Royer, J.E. Knapp, K. Strand and H.A. Heaslet (2001) “Cooperative hemoglobins: conserved fold, diverse quaternary assemblies and allosteric mechanisms” Trends in Biochem. Sci. 26, 297-304

H.A. Heaslet and W.E. Royer (2001) “Crystalline ligand transitions in lamprey hemoglobin: structural evidence for the regulation of oxygen affinity” J. Biol. Chem. 276, 26230-26236

J.E. Knapp, Q.H. Gibson, L. Cushing and W.E. Royer (2001) “Restricting the ligand-linked heme movement in Scapharca dimeric hemoglobin reveals tight coupling between distal and proximal contributions to cooperativity” Biochemistry 40, 14795-14805

J.E. Knapp and W.E. Royer (2003) “Ligand-linked structural transitions in crystals of a cooperative dimeric hemoglobin” Biochemistry 42, 4640-4647

K. Strand, J.E. Knapp, B. Bhyravbhatla and W.E. Royer (2004) “Crystal Structure of the hemoglobin dodecamer from Lumbricus erythrocruorin: Allosteric core of giant annelid respiratory complexes”, J. Mol. Biol. 344 , 119-134

J.F. Flores, C.R. Fisher , S.L. Carney, B.N. Green, J.K. Feytag, S.W. Schaeffer and W.E. Royer (2005) “Sulfide binding is mediated by zinc ions discovered in the crystal structure of a hydrothermal vent tubeworm hemoglobin”, PNAS 102, 2713-2718

W.E. Royer, H. Zhu, T.A. Gorr, J.F. Flores, J.E. Knapp (2005) “Allosteric hemoglobin assembly: Diversity and similarity”, J. Biol. Chem. 280, 27477-27480

J.E. Knapp, M.A. Bonham, Q.H. Gibson, J.C. Nichols and W.E. Royer (2005) “Residue F4 plays a key role in modulating oxygen affinity and cooperativity in Scapharca dimeric hemoglobin”, Biochemistry 44, 14419-14430

J.E. Knapp, R. Pahl, V. Š rajer and W.E. Royer (2006) “Allosteric action in real time: nanosecond time-resolved crystallographic studies of a cooperative dimeric hemoglobin” Proc. Natl. Acad. Sci. (USA) 103, 7649-7654

W.E. Royer, H. Sharma, K. Strand, J.E. Knapp and B. Bhyravbhatla (2006) “Lumbricus erythrocruorin at 3.5Å resolution: Architecture of a megadalton respiratory complex”, Structure 14, 1167-1177

J.C. Nichols, W.E. Royer, Q.H. Gibson (2006) “An optical signal correlated with the allosteric transition in Scapharca inaequivalvis HbI” Biochemistry45, 15748-15755

W.E. Royer, M.N. Omartian and J.E. Knapp (2007) “Low resolution structure of Arenicola erythrocruorin:  Influence of coiled coils on the architecture of a megadalton respiratory protein” J. Mol. Biol. 365, 226-236

W. Chen, S.S. Lam, H. Srinath  , C.A. Schiffer, W.E. Royer, K. Lin (2007) “Competition between Ski and CREB-binding protein for binding to Smad Proteins in Transforming Growth Factor-b signaling” J. Biol. Chem.282, 11365-11376

V. Šrajer and W.E. Royer (2008) “Time-resolved x-ray crystallography of heme proteins” Methods Enzymol. 437, 379-395

W. Chen, H. Srinath, S.S. Lam,  C.A. Schiffer, W.E. Royer, K. Lin (2008) “Contribution of Ser386 and Ser396 to activation of interferon regulatory factor 3” J. Mol. Biol. 379, 251-260

W. Chen, S.S. Lam,  H. Srinath, Z. Jiang, J.J. Correia, C.A. Schiffer, K.A. Fitzgerald, K. Lin, W.E. Royer (2008) “Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5” Nature Struct. & Mol. Biol.., 15, 1213-1220