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Alonzo Ross, Ph.D.
Academic Role: Professor
Faculty Appointment(s) In:
Biochemistry and Molecular Pharmacology
Other Affiliation(s):
Interdisciplinary Graduate Program
Program in Neuroscience
Representative Publications
Lachyankar, M.B., Sultana, N., Schonhoff, C.M., Mitra, P., Poluha, W., Lambert, S., Quesenberry, P.J., Litofsky, N.S., Nabi, R., Recht, L.D., Miller, S.J., Ohta, S., Neel, B.G., and Ross, A.H. (2000). A role for PTEN in neuronal differentiation. J. Neurosci. 20: 1404-1413.
Li, L., Liu, F., Salmonsen, R.A., Turner, T.K., Litofsky, N.S., Di Cristofano, A., Pandolfi, P.P., Jones, S.N., Recht, L.D., and Ross, A.H. 2002. PTEN in neural precursor cells: regulation of migration, apoptosis and proliferation. Mol. Cell. Neurosci. 20, 21-29.
Schonhoff, C.M., Daou, M.-D., Jones, S.N., Schiffer , C.A. , and Ross, A.H. 2002. Nitric oxide inhibits Hdm2-p53 binding through nitrosylation of Hdm2. Biochemistry 41, 13570-13574.
Lachyankar, M.B., Condon, P.J., Daou, M.-C., De, A.K., Levine, J.B., Obermeier, A., and Ross, A.H. 2003. Novel, functional interactions between Trk kinase and p75 neurotrophin receptor in neuroblastoma cells. J. Neurosci. Res. 71, 157-172.
Li, L., Liu, F., and Ross, A.H. 2003. PTEN regulation of neural development and CNS stem cells (Invited review). J. Cell. Biochem. 88, 24-28.
Campbell , R.B., Liu, F., and Ross, A.H. 2003. Allosteric activation of PTEN phosphatase by phosphatidylinositol 4,5-bisphosphate. J. Biol. Chem. 278, 33617-33620.
Li, L., He, F., Litofsky , N.S. , Recht, L.D., and Ross, A.H. 2003. Profiling of genes expressed by PTEN haploinsufficient neural precursor cells. Mol. Cell. Neurosci. 24, 1051-1061.
Greco, B., Low, H.P., Johnson, E.C., Salmonsen, R.A., Gallant, J., Jones, S.N., Ross, A.H., and Recht, L.D. 2004. Differentiation prevents assessment of neural stem cell pluripotency after blastocyst injection . Stem Cells 22, 600-608.
Mitra, P., Zhang, Y., Rameh, L.E., Ivshina, M.P., McCollum, D., Nunnari, J.J., Hendricks, G.M., Kerr, M.L., Field, S.J., Cantley, L.C., and Ross, A.H. 2004. A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast. J. Cell Biol. 166, 205-211.
Daou, M.C., Smith, T.W., Litofslcy, N.S., Hsieh, C.C., and Ross, A.H. 2005 Double cortin is preferentially expressed in invasive humain brain tumors. Acta Neuropathol. 110, 472 - 480.
Redfern, R.E., Redfern, D., Furgason, M.L.M., Munson, M., Ross, A.H., and Gericke, A. 2008. PTEN phosphatase selectively birds phosphoinositides and undergoes structural change. Biochemistry 47, 2162 - 2171.
Li, L., Dutra, A., Pak, E., Labrie, J.E., Gerstein, R.M., Pandolfi, P.P., Recht, L.D., and Ross, A.H. 2009. EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors. Neuro-Oncology 11, 9-21.
Office: LRB-819, Lab 870 I-K
Phone: 508-856-8016
E-mail: Alonzo.Ross@umassmed.edu
Keywords:
Neurobiology,
Cancer Biology,
Stem Cell Biology,
Biochemistry,
Oncogenes/tumor suppressors
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