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Oliver J. Rando, Ph.D.,M.D.
Academic Role: Assistant Professor
Faculty Appointment(s) In:
Biochemistry and Molecular Pharmacology
Publications
Research
Dennis, J.H., Fan, H.Y., Reynolds, S.M., Yuan, G., Meldrim, J.C., Richter, D.J., Peterson, D.G., Rando, O.J., Noble, W.S., Kingston, R.E. “Independent and complementary methods for large-scale structural analysis of mammalian chromatin”, Genome Res 2007, 17, 928-39.
Dion, M.F., Kaplan, T., Kim, M., Buratowski, S., Friedman, N., Rando, O.J. “Dynamics of replication-independent histone turnover in budding yeast”, Science 2007, 315, 1405-8.
Kim, M., Vasiljeva, L., Rando, O.J., Zhelkovsky, A., Moore, C., Buratowski, S. “Distinct pathways for snoRNA and mRNA termination”, Mol Cell 2006, 24, 723-34.
Raisner, R.M., Hartley, P.D., Meneghini, M.D., Bao, M.Z., Liu, C.L., Schreiber, S.L., Rando, O.J., Madhani, H.D. “Histone variant H2A.Z marks the 5’ ends of both active and inactive genes in euchromatin”, Cell 2005, 123: 233-48
Liu, C.L., Kaplan, T., Kim, M., Buratowski, S., Schreiber, S.L., Friedman, N., Rando, O.J. “Single-nucleosome mapping of histone modifications in S. cerevisiae”, PLoS Biology 2005, 3: e328.
Yuan, G.C., Liu, Y.J., Dion, M.F., Slack, M.D., Wu, L.F., Altschuler, S.J., Rando, O.J. “Genome-scale identification of nucleosome positions in S. cerevisiae”, Science 2005, 309: 626-30.
Casolari, J.M., Brown, C.R., Drubin, D.A., Rando, O.J., Silver, P.A. “Developmentally induced changes in transcriptional program alter spatial organization across chromosomes”, Genes Dev 2005, 19: 1188-98.
Dion, M.F., Altschuler, S.J., Wu, L.F., Rando, O.J. “Genomic characterization reveals a simple histone H4 acetylation code”, PNAS 2005, 102: 5501-06.
Kim, M., Krogan, N.J., Vasiljeva, L., Rando, O.J., Nedea, E., Greenblatt, J.F., Buratowski, S. “The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II”, Nature 2004, 432: 517-22.
Diehn, M.*, Alizadeh, A.A.*, Rando, O.J.*, Liu, C.L.*, Stankunas, K., Botstein, D., Crabtree, G.R., Brown, P.O. “Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation”, PNAS 2002, 99: 11796-801. * Indicates authors contributing equally.
Rando, O.J., Zhao, K., Janmey, P., Crabtree, G.R. “Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex”, PNAS 2002, 99: 2824-9.
Zhao, K., Wang, W., Rando, O.J., Xue, Y., Swiderek, K., Kuo, A., Crabtree, G.R. “Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling”, Cell 1998, 95: 625-36.
Palombella, V.J., Rando, O.J., Goldberg, A.L., Maniatis, T. “The ubiquitin-proteasome system is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B”, Cell 1994, 78: 773-85.
Reviews
Rando, O.J., Ahmad, K. “Rules and regulation in the primary structure of chromatin”, Curr Opin Cell Biol 2007, 19, 250-6.
Rando, O.J., Verstrepen, K.J. “Time scales of genetic and epigenetic inheritance”, Cell 2007, 128, 655-68.
Rando, O.J. “Global patterns of histone modifications”, Curr Opin Genet Dev 2007, 17, 94-9.
Rando, O.J. “Chromatin structure in the genomic era”, Trends Genet 2007, 23, 67-73.
Rando, O.J., Paulsson, J. “Noisy silencing of chromatin”, Dev Cell 2006, 11: 134-6
Rando, O.J., Chi, T., Crabtree, G.R. “Second messenger control of chromatin remodeling”, Nat Struct Biol 2003, 10: 81-3
Rando, O.J., Zhao, K., Crabtree, G.R. “Searching for a function for nuclear actin”, Trends Cell Biol. 2000, 10: 92-97.
Office: LRB 903
Phone: 508-856-8879
E-mail: Oliver.Rando@umassmed.edu
Keywords:
Stem Cell Biology,
Chromosome Structure & Dynamics,
Systems Biology,
Gene Expression,
Genomics
Postdoctoral Position Available
A postdoctoral position is available to study in this laboratory. Contact Dr. Rando for additional details.
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