Section: Publications

Tariq Rana, Ph.D.

Other Affiliation(s):
   Center for AIDS Research

Representative Publications

Robb G.B., Rana, T. M.  (2007)  RNA Helicase A Interacts with RISC in Human Cells and Functions in RISC Loading.  Mol Cell, 26, 523-537

Baigude H, McCarroll J, Yang C.S., Swain P.M., Rana T. M.  (2007)   Design and creation of new nanomaterials for therapeutic RNAi.  ACS Chem Biol. 2, 237-41.

Rana, T. M.  (2007)  Illuminating the silence: understanding the structure and function of small RNAs.  Nat Rev Mol Cell Biol. 8, 23-36.

Ali A., Reddy G.S., Cao H., Anjum S.G., Nalam M.N., Schiffer C.A., Rana T. M.  (2006)  Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands.  J Med Chem. 49, 7342-56.

Chu, C.Y. and Rana, T. M.  (2006) Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54.  PLoS Biol, 4, e210

Wichroski, M.J., Robb, G.B., and Rana, T. M.  (2006) Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies.  PLoS Pathog, 2, e41

Chiu, Y.L., Dinesh, C.U., Chu, C.Y., Ali, A., Brown, K.M., Cao, H., and Rana T.M.  (2005) Dissecting RNA-interference pathway with small molecules.  Chem Biol, 12, 643

Brown, K.M., Chu, C.Y., and Rana, T. M.  (2005) Target accessibility dictates the potency of human RISC.  Nat Struct Mol Biol, 12, 469

Robb, G.B., Brown, K.M., Khurana, J., and Rana, T.M.  (2005) Specific and potent RNAi in the nucleus of human cells.  Nat Struct Mol Biol, 12, 133

Wichroski, M.J., Ichiyama, K., and Rana, T. M.  (2005) Analysis of HIV-1 viral infectivity factor-mediated proteasome-dependent depletion of APOBEC3G: correlating function and subcellular localization.  J Biol Chem, 280, 8387     

Hwang, S., Tamilarasu, N., Kibler, K., Cao, H., Ali, A., Ping, Y-P., Jeang, K-T., and Rana, T. M. (2003) Discovery of a Small Molecule Tat-trans-Activation-responsive RNA Antagonist That Potently Inhibits Human Immunodeficiency Virus-1 Replication.   J Biol Chem, 278, 39092

Chiu, Y-L., and Rana, T. M. (2002) RNAi in human cells: basic structural and functional features of small interfering RNA.   Mol Cell, 10, 549

Chiu, Y-L., Ho, C. K., Saha, N., Schwer, B., Shuman, S., and Rana, T. M. (2002) Tat stimulates cotranscriptional capping of HIV mRNA.  Mol Cell, 10, 585

Richter, S., Ping, Yueh-Hsin., and Rana, T. M. (2002) TAR RNA loop: A scaffold for the assembly of a regulatory switch in HIV replication.   PNAS, 99, 7928

Office: LRB 827, Lab 860 A-E
Phone: 508-856-6216
E-mail: Tariq.Rana@umassmed.edu
Keywords: Pharmacology, Biochemistry, Chemical Biology

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