Thoru Pederson, Ph.D.
Academic Role: Professor
Faculty Appointment(s) In:
Biochemistry and Molecular Pharmacology
Other Affiliation(s):
Cell Dynamics Group
Interdisciplinary Graduate Program
Selected Recent Publications
Politz, J.C.R., F. Zhang and T. Pederson. (2006) miR-206 co-localizes with ribosome-rich regions in the nucleolus and cytoplasm of rat myogenic cells. Proc. Natl. Acad. Sci. USA 103: 18957-18962. 17135348
Ritland Poland, J.C., I. Polena, I. Trask, D.P. Bazett-Jones and T. Pederson. (2005) A non-ribosomal landscape in the nucleolus revealed by the stem cell protein nucleostemin. Mol.Biol.Cell, 16: 3401-3410. 15857956
Sommerville, J., C.L. Brumwell, Ritland Politz, J.C. and T. Pederson. (2005) Signal recognition particle assembly in relation to the function of amplified nucleoli in Xenopus oocytes. J. Cell Sci. 118:1299-1307. 15741230
Politz, J.C., R.A. Tuft, and T. Pederson. (2004). Photoactivation-based labeling and in vivo tracking of RNA molecules in the nucleus. In Live Cell Imaging: A Laboratory Manual. Cold Spring Harbor Laboratory Press, 177-185.
Pederson, T. (2004). The spatial organization of the genome in mammalian cells. Curr. Opin. Genet. Dev.14: 203-209. 15196468
Pederson, T. (2004). Can telomerase be put in its place? J. Cell Biol.164: 637-639. 14993231
Pederson, T. (2004). RNA interference and mRNA silencing, 2004: how far will they reach? Mol. Biol. Cell 15: 407-410. 14657237
Politz, J.C., R.A. Tuft, and T. Pederson (2003). Diffusion-based transport of nascent ribosomes in the nucleus. Mol. Biol. Cell 14: 4805-4812. 12960421
Wang, C., J.C. Politz, T. Pederson and S. Huang (2003). RNA polymerase III transcripts and the PTB protein are essential for the integrity of the perinucleolar compartment. Mol. Biol. Cell 14: 2425-2435. 12808040
Politz, J.C., L.B. Lewandowski and T. Pederson (2002). Signal recognition particle RNA localization within the nucleolus differs from the classical sites of ribosome synthesis. J. Cell Biol. 159: 411-418. 12427865
Mougin, A., F. Torterotot, C. Branlant, M.R. Jacobson, Q. Huang and T. Pederson (2002). A 3'-terminal minihelix in the precursor of human spliceosomal U2 small nuclear RNA. J. Biol. Chem. 277: 23137-23142. 11956214
Yarovoi, S.V. and T. Pederson (2001). Human cell lines expressing hormone regulated T7 RNA polymerase localized at distinct intranuclear sites. Gene 275: 73-81. 11574154
Pederson, T. (2001). Protein mobility within the nucleus -- what are the right moves? Cell 104: 635-638. 11257216
Pederson, T. (2001). Fluorescent RNA cytochemistry: tracking gene transcripts in living cells. Nucleic Acids Res. 29: 1013-1016. 11222750
Pederson, T. (2000). Diffusional protein transport within the nucleus: a message in the medium. Nature Cell Biol. 2: E73-E74. 10806486
Politz, J.C. and T. Pederson (2000). Movement of mRNA from transcription site to nuclear pores. J. Struct. Biol. 129: 252-257. 10806075
Pederson, T. and J.C. Politz (2000). The nucleolus and the four ribonucleoproteins of translation. J. Cell Biol. 148: 1091-1095. 10725320
Pederson, T. (2000). Half a century of “the nuclear matrix”. Mol. Biol. Cell 11: 799-805. 10712500
Politz, J.C., S. Yarovoi, S.M. Kilroy, K. Gowda, C., Zwieb and T. Pederson (2000). Signal recognition particle components in the nucleolus. Proc. Natl. Acad. Sci. USA 97: 55-60. 10618370
Politz, J.C., R.A. Tuft, T. Pederson and R.H. Singer (1999). Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells. Curr. Biol. 9:285-291. 10209094
Huang, Q. and T. Pederson (1999). A human U2 RNA mutant stalled in 3' end processing is impaired in nuclear import. Nucleic Acids Res. 27: 1025-1031. 9927735
Pederson, T. (1998). The plurifunctional nucleolus. Nucleic Acids Res. 26: 3871-3876. 9705492
Jacobson, M.R. and T. Pederson (1998). Localization of signal recognition particle RNA in the nucleolus of mammalian cells. Proc. Natl. Acad. Sci.USA 95: 7981-7986. 9653126
Politz, J.C., E.S. Browne, D.E. Wolf and T. Pederson (1998). Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells. Proc. Natl. Acad. Sci.USA 95: 6043-6048. 9600914
Office: B4-337
Phone: 508-856-8667
Fax: 508-856-8668
E-mail: Thoru.Pederson@umassmed.edu
Keywords:
RNA Biology,
Stem Cell Biology,
Gene Expression,
Nuclear Architecture,
RNA Interference (RNAi)
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