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Mary Munson, Ph.D.
Academic Role: Assistant Professor
Faculty Appointment(s) In:
Biochemistry and Molecular Pharmacology
Other Affiliation(s):
Cell Biology
Cell Dynamics Group
Interdisciplinary Graduate Program
Representative Publications
M. Munson. “Tip20p reaches out to Dsl1p to tether membranes .” Nature Struct Mol Biol, 16:100-102, 2009.
N. Croteau, M.L.M. Furgason, D. Devos and M. Munson. “Conservation of helical bundle structure between the exocyst subunits. ” PLoS ONE, 4:e4443, 2009.
M. Munson and N.J. Bryant. “A role for the syntaxin N-terminus .” Biochem J, 418:e1-3, 2009.
J. Songer and M. Munson. “Sec6p anchors the exocyst complex at sites of secretion .” Mol Biol Cell, 20:973-982, 2009.
C.M. Carr and M. Munson (2007). “Tag team action at the synapse .” EMBO Reports, 8:834-8
J. Togneri, Y.S. Cheng, M. Munson, F.M. Hughson and C.M. Carr (2006). “Specific SNARE complex binding mode of the Sec1/Munc-18 protein, Sec1p. ” Proc Natl Acad Sci USA, 103:17730-5.
M.V.S. Sivaram, M.L.M. Furgason, D.N. Brewer, and M. Munson (2006). “The structure of the exocyst subunit Sec6p defines a conserved architecture with diverse roles .” Nat Struct Mol Biol, 13:555-556.
M. Munsonand P. Novick (2006). “The Exocyst defrocked, a framework of rods revealed .” Nat Struct Mol Biol, 13: 577-581.
X. Pan, S. Eathiraj, M. Munson, and D.G. Lambright (2006). “TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism. ” Nature, 442:303-306.
A. Gericke, M. Munson, and A.H. Ross (2006). “Regulation of the PTEN phosphatase .” Gene, 374:1-9.
M.V.S. Sivaram, J.A. Saporita, M.L.M. Furgason, A.J. Boettcher, and M. Munson (2005),Dimerization of the exocyst protein Sec6p and its interaction with the t-SNARE Sec9p . Biochemistry. 44: 6302–6311.
M. Munson and F.M. Hughson (2002), Conformational regulation of SNARE assembly and disassembly in vivo. J Biol Chem, 277: 9375-9381 .
M. Munson*, X. Chen*, S. Schultz, A.E. Cocina, and F.M. Hughson (2000) "Interactions within the yeast t-SNARE Sso1p that control SNARE complex assembly ." Nature Structural Biology. 7: 894-902 .
C.M. Carr, E. Grote, M. Munson, F.M. Hughson and P.J. Novick (1999) "Sec1p Binds to SNARE Complexes and Concentrates at Sites of Secretion. " J Cell Biology. 146: 333-344.
K.L. Nicholson, M. Munson, R.B. Miller, T.J. Filip, R. Fairman, and F.M. Hughson (1998) "Regulation of SNARE complex assembly by an N-terminal domain of the t-SNARE Sso1p. " Nature Structural Biology. 5: 793-802.
M.W. Klemba*, M. Munson*, and L. Regan. (1998) "De novo design of protein structure and function." In: Proteins: Analysis and Design. (Ed. by R.H. Angeletti), Academic Press, N.Y., N.Y.
M. Munson, K. Anderson, and L. Regan (1997) "Speeding up protein folding: mutations that increase the rate at which Rop folds and unfolds by over four orders of magnitude ." Folding & Design 2: 77-87.
M. Munson, S. Balasubramanian, K.G. Fleming, A.D. Nagi, R. O' Brien, J.M. Sturtevant and L. Regan (1996) "What makes a protein a protein? Hydrophobic core designs that specify stability and structural properties. " Protein Science 5: 1584-1593.
C.K. Smith, M. Munson, and L. Regan (1995) "Studying a-helix and b-sheet formation in small proteins." In: Techniques in Protein Chemistry, Vol VI, p. 323-332.
M. Munson, R. O'Brien, J.M. Sturtevant, and L. Regan (1994) "Redesigning the hydrophobic core of a four-helix-bundle protein. " Protein Science 3: 2015-2022.
M. Munson, P.F. Predki, and L. Regan (1994) "ColE1-compatible vectors for high-level expression of cloned DNAs from the T7 promoter. " Gene 144: 59-62.
(* indicates authors contributed equally)
Office: LRB 905, Lab 970-Y, 940 A
Phone: 508-856-8318
E-mail: Mary.Munson@umassmed.edu
Keywords:
Intracellular Trafficking,
Biophysics,
Cell Biology,
Biochemistry,
Structural Biology
Postdoctoral Position Available
A postdoctoral position is available to study in this laboratory.
Contact Dr. Munson for additional details.
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