Section: Publications

William Kobertz, Ph.D.

Academic Role: Associate Professor

Faculty Appointment(s) In:
   Biochemistry and Molecular Pharmacology

Other Affiliation(s):
   Interdisciplinary Graduate Program
   Program in Neuroscience

Representative Publications

Mruk K and Kobertz WR.  (2009) Discovery of a Novel Activator of KCNQ1-KCNE1 K+ Channel Complexes .  PLoS ONE 4, e4236.

Ahern CA and Kobertz WR.  (2009) Chemical Tools for K+ Channel Biology .  Biochemistry 48, 517-526.

Morin TJ and Kobertz WR.  (2008) Tethering chemistry and K+ Channels.    J. Biol. Chem. 283, 25105-25109.

Morin TJ and Kobertz WR  (2008)  Counting Membrane-embedded KCNE b-subunits in Functioning K+ Channel Complexes.   Proc. Natl. Acad. Sci. USA.  105, 1478-1482.

Rochelau JM and Kobertz WR.  (2008)   KCNE Peptides Differently Affect Voltage Sensor Equilibrium and Equilibration Rates in KCNQ1 K+ Channels.   J. Gen. Physiol. 131, 59-68. 

Morin TJ and Kobertz WR.  (2007)  A Derivatized Scorpion Toxin Reveals the Functional Output of Heteromeric KCNQ1-KCNE K+ Channel Complexes.   ACS Chem Biol. 2, 469-473.  (Point of View / July 2007 Podcast )

Chandrasekhar KD, Bas T and Kobertz WR. (2006)  KCNE1 Subunits Require Co-assembly with K+ Channels for Efficient Trafficking and Cell Surface Expression.    J. Biol. Chem. 281, 40015-40023.

Rocheleau JM, Gage SD and Kobertz WR. (2006)  Secondary structure of a KCNE cytoplasmic domain.   J. Gen. Physiol. 128, 721-729.

Gage, SD and Kobertz WR.  (2004)  KCNE3 Truncation Mutants Reveal a Bipartite Modulation of KCNQ1 K+ Channels. J. Gen. Physiol. 124, 759-771.

Kobertz, WR, Williams, C and Miller, C. (2000)  Hanging Gondola Structure of the T1 Domain in a Voltage-gated K+ channel.   Biochemistry 39, 10347-10352.

Kobertz, WR and Miller, C. (1999)  K+ Channels Lacking the "Tetramerization" Domain: Implications for Pore Structure.   Nat. Struct. Biol. 6, 1122-1125.

Office: LRB 804, lab 840A-C
Phone: 508-856-8861
E-mail: William.Kobertz@umassmed.edu
Keywords: Biophysics, Ion Channels, Biochemistry, Membrane Protein Structure & Function, Chemical Biology

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