|
|
|
Michael Green, Ph.D.,M.D.
Academic Role: Professor
Faculty Appointment(s) In:
Program in Gene Function and Expression
Program in Molecular Medicine
Joint Faculty In:
Biochemistry and Molecular Pharmacology
Other Affiliation(s):
Center for AIDS Research
Interdisciplinary Graduate Program
Relevant Recent Publications
Santra, M.K., Wajapeyee, N. and Green, M.R. (2009) F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage. Nature, 459: 722-725.
Sheng, Z., Wang, S.Z. and Green, M.R. (2009) Transcription and signalling pathways involved in BCR-ABL-mediated misregulation of 24p3 and 24p3R. EMBO J., 28: 866-876.
Gobeil, S., Zhu, X., Doillon, C.J. and Green, M.R. (2008) A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene. Genes Dev., 22: 2932-2940.
Shen, H., Zheng, X., Shen, J., Zhang, L., Zhao, R. and Green, M.R. (2008) Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Genes Dev., 22: 1796-1803.
Wajapeyee, N., Serra, R.W., Zhu, X., Mahalingam, M. and Green, M.R. (2008) Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell, 132: 363-374.
Hart, D.O., Raha, T., Lawson, N.D. and Green, M.R. (2007) Initiation of zebrafish hematopoiesis by the TATA-box-binding protein-related factor Trf3. Nature, 450: 1082-1085.
Gazin, C., Wajapeyee, N., Gobeil, S., Virbasius, C-M. and Green, M.R. (2007) An elaborate pathway required for Ras-mediated epigenetic silencing. Nature, 449: 1073-1077.
Shen, H. and Green, M.R. (2007) RS domain-splicing signal interactions in splicing of U12-type and U2-type introns. Nat. Struct. Mol. Biol., 14: 597-603.
Teodoro, J.G., Parker, A.E., Zhu, X. and Green, M.R. (2006) p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase. Science, 313: 968-971.
Devireddy, L.R., Gazin, C., Zhu, X. and Green, M.R. (2005) A cell surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake. Cell 123:1293-1305.
Office: LRB-628
Phone: 508-856-5330
E-mail: Michael.Green@umassmed.edu
Keywords:
RNA Splicing,
Cancer Biology,
Apoptosis,
Gene Expression,
Gene Regulation
Postdoctoral Position Available
A postdoctoral position is available to study in this laboratory.
Contact Dr. Green for additional details.
|
|
|