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Section: Publications

Sumner Burstein, Ph.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Biochemistry and Molecular Pharmacology

Other Affiliation(s):
   Medicine

Publications

Burstein S, Salmonsen R 2008. Acylamido analogs of endocannabinoids selectively inhibit cancer cell proliferation. Bioorg Med Chem doi:10.1016/j.bmc.2008.10.015.

Stebulis, Judith A., Johnson, David R., Rossetti, Ronald G., Burstein, Sumner H., Zurier, Robert B., Ajulemic acid, a synthetic cannabinoid acid, induces an antiinflammatory profile of eicosanoids in human synovial cells, Life Sciences (2008), doi: 10.1016/j.lfs.2008.09.004

Rimmerman N, Bradshaw HB, Hughes HV, Chen JS, Hu SS, McHugh D, Vefring E, Jahnsen JA, Thompson EL, Masuda K, Cravatt BF, Burstein S, Vasko MR, Prieto AL, O'Dell DK, Walker JM. N-Palmitoyl Glycine, a Novel Endogenous Lipid That Acts as a Modulator of Calcium Influx and Nitric Oxide Production in Sensory Neurons. Mol Pharmacol 2008.

Burstein, S. The elmiric acids: biologicaly active anandamide analogs, europharmacology (2007), doi: 10.1016/j.neuropharm.2007.11.011

Ambrosio, A. L., Dias, S. M., Polikarpov, I., Zurier, R. B., Burstein, S. H., Garratt, R. C., 2007. Ajulemic Acid, a Synthetic Nonpsychoactive Cannabinoid Acid, Bound to the Ligand Binding Domain of the Human Peroxisome Proliferator-activated Receptor {gamma}. J Biol Chem 282, 18625-18633.

Burstein, S. H., Adams, J. K., Bradshaw, H. B., Fraioli, C., Rossetti, R. G., Salmonsen, R. A., Shaw, J. W., Walker, J. M., Zipkin, R. E., Zurier, R. B., 2007. Potential anti-inflammatory actions of the elmiric (lipoamino) acids. Bioorg Med Chem 15, 3345-3355.

Johnson, D. R., Stebulis, J. A., Rossetti, R. G., Burstein, S. H., Zurier, R. B., 2007. Suppression of fibroblast metalloproteinases by ajulemic acid, a nonpsychoactive cannabinoid acid. J Cell Biochem 100, 184-190.

M. G. Cascio, A. Minassi, A. Ligrest, G. Appendino, S. H. Burstein and V. Di Marzo M. G. Cascio, A. Minassi, A. Ligrest, G. Appendino, S. H. Burstein and V. Di Marzo A structure activity relationship study on N-arachidonoyl-aminoacids as possible endogenous inhibitors of fatty acid amide hydrolase. Biochem Biophys Res Commun. (2004) 30; 314(1): 192-6.

M.Karst, K.Salim, S.Burstein, I.Conrad, L.Hoy and U.Schneider. (2003) Analgesic effect of the synthetic cannabinoid 1`,1`dimethylheptyl-delta8-THC-11-oic acid (CT-3) on chronic neuropathic pain in man. JAMA  290(13):1757-1762

Bidinger B, Torres R, Rossetti RG, Brown L, Beltre R, Burstein S, Lian JB, Stein GS, Zurier RB. Ajulemic acid. A non psychoactive cannabinoid acid, induces apoptosis in human T lymphocytes. (2003) Clin Immunol. 108(2):95-102.

J. Liu, H. Li, S. H. Burstein, J. D. Chen. (2003) Ajulemic Acid, a synthetic non-psychoactive cannabinoid, is an Activator for Peroxisome Proliferator-Activated Receptor g. Mol Pharmacol.63: 983-992

S. H. Burstein, S. M. Huang,T. J. Petros, R. G. Rossetti, J.M. Walker and R. B. Zurier. (2002) Regulation of anandamide tissue levels by N-arachidonylglycine. Biochem Pharmacol 64:1147-50.

R. B. Zurier, R.G. Rossetti, S. H. Burstein and B. Bidinger. Suppression of human monocyte Interleukin-1bproduction by ajulemic acid, a non-psychoactive cannabinoid. (2003) Biochem Pharmacol. 65: 649-655

L.D.Recht ,R. Salmonsen ,R. Rosetti., T. Jang ,G. Pipia , T. Kubiatowski , P. Karim., A. H. Ross , R. Zurier, N.S. Litofsky, S. Burstein.Antitumor Effects of Ajulemic Acid (CT3), a synthetic non-psychoactive cannabinoid, Biochem. Pharmacol. 62: 755-763 (2001).

S. Huang SM, Bisogno T, Petros TJ, Chang SY, Zavitsanos PA, Zipkin RE, Sivakumar R, Coop A, Maeda DY, De Petrocellis L, Burstein S, Di Marzo V and Walker JM (2001) Identification of a New Class of Molecules, the Arachidonyl Amino Acids, and Characterization of One Member That Inhibits Pain. J Biol Chem. 276:42639-42644.

 


Office: Research 803, Lab 870W
Phone: 508-856-2850
E-mail: Sumner.Burstein@umassmed.edu

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