Section: Publications

Postdoctoral Position Available

Dan Bolon, Ph.D.

Academic Role: Assistant Professor

Faculty Appointment(s) In:
   Biochemistry and Molecular Pharmacology

Selected Publications

Haririnia A., Verma R., Purohit N., Twarog M.Z., Deshaies R.J., Bolon D., Fushman D. (2008) Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins. J. Mol. Biol., 375:979-996. [abstract in Pubmed]

Wayne N., Bolon D. N. (2007) Dimerization of Hsp90 is required for in vivo function: design and analysis of monomers and dimers. J. Biol. Chem., 282:35386-35395. [abstract in Pubmed]

Bolon D. N., Grant R. A., Baker T. A., and Sauer R. T. (2005) Specificity versus stability in computational protein design. Proc. Natl. Acad. Sci. USA, 102, 12724-12729. [abstract in Pubmed]

Bolon D. N., Grant R. A., Baker T. A., and Sauer R. T. (2004) Nucleotide-dependent substrate handoff from the SspB adaptor to the AAA+ ClpXP protease. Mol. Cell, 16, 443-450. [abstract in Pubmed]

Bolon D. N., Wah D. A., Hersch G. L., Baker T. A., and Sauer R. T. (2004) Bivalent tethering of SspB to ClpXP is required for efficient substrate delivery: a protein-design study. Mol. Cell, 13, 443-449. [abstract in Pubmed]

Bolon D. N., Marcus J. S., Ross S. A., and Mayo S. L. (2003) Prudent modeling of core polar residues in computational protein design. J. Mol. Biol., 329, 611-622. [abstract in Pubmed]

Bolon D. N. and Mayo S. L. (2001) Enzyme-like proteins by computational protein design. Proc. Natl. Acad. Sci. USA, 98, 14274-14279. [abstract in Pubmed]

Bolon D. N. and Mayo S. L. (2001) Polar residues in the protein core of E. coli thioredoxin are important for fold specificity. Biochemistry, 40, 10047-10053. [abstract in Pubmed]

Reviews

Sauer, R.T., Bolon, D.N., Burton, B.M., Burton, R.E., Flynn, J.M., Grant, R.A., Hersch, G.L., Joshi, S.A., Kenniston, J.A., Levchenko, I., Neher S.B., Siddiqui, S.M., Wah, D.A. & Baker, T.A. (2004) Sculpting the proteome with AAA+ proteases and disassembly machines. Cell, 119, 9-18. [abstract in Pubmed]

Bolon D. N., Voigt C. A. and Mayo S.L. (2002) De novo design of biocatalysts. Curr. Opin. Chem. Biol., 6, 125-129. [abstract in Pubmed]

Office: LRB 922
Phone: 508-856-3588
Fax: 508-856-6231
E-mail: Dan.Bolon@umassmed.edu
Keywords: Protein Folding, Biophysics, Structural Biology, Biochemistry, Systems Biology

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Postdoctoral Position Available  A postdoctoral position is available in this laboratory, experience with deep sequencing and or yeast biology is desired. Contact Dr. Bolon for additional details.