Section: Research

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Richard Tuft, Ph.D.

Academic Role: Research Associate Professor

Faculty Appointment(s) In:
   Physiology

Other Affiliation(s):
   Biomedical Engineering and Medical Physics

Development of New Optical/Electronic Microscopes

My current research interest is the development of new optical/electronic microscopes, and their application to the problems of imaging rapid changes in the concentration of intracellular ions and molecules. A microscope incorporating fast piezoelectric focusing (at 1 micrometer per millisecond), a low-noise high-quantum-efficiency solid state CCD camera, and ultraviolet and visible laser illumination is currently being used to study intracellular [Ca²⁺] near the plasma membrane of smooth muscle cells, the role of Ca²⁺ and other second messengers in the chemotaxis of white blood cells, and [Ca²⁺] dynamics in secretory cells.

Office: Biotech II, Suite 114
Phone: 508 856 2383
E-mail: Richard.Tuft@umassmed.edu
Keywords: Biophysics, Electrophysiology, Imaging and Microscopy

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