Postdoctoral Position Available
Please contact Dr. Weng directly for more information regarding this post-doctoral position.
Postdoc Position in Comparative Genomics
The laboratories of Profs. Zhiping Weng (Bioinformatics) and Bob Brown (Neurology) at University of Massachusetts Medical School (UMMS) invite applications for a postdoc position in comparative genomics. In an NIH-funded project undertaken jointly with Dr. David Goldstein (Director, Center for Human Genome Variation, Institute for Genome Sciences & Policy, Duke University), the Brown lab will perform whole genome sequencing with the Solexa platform on 40 amyotrophic lateral sclerosis (ALS) patients.
The postdoc will develop and apply computational tools to analyze this wealth of sequence data and identify genetic variations among the individuals and prioritize them with other functional data, such as those generated with the HapMap and ENCODE projects. Subsequently, the Brown lab will genotype the prioritized variations in cohorts of 1,000 cases and 1,000 controls, and the postdoc will participate in the analysis of the resulting data to discover determinants of susceptibility and phenotype.
An ideal candidate would have a PhD in computational biology, bioinformatics, computer science, or another quantitative field and have substantial experience in analyzing high-throughput genomics data. Excellent programming skills and statistics knowledge are essential.
UMMS is a highly collaborative research environment and Profs. Weng and Brown have recently been recruited to UMMS to establish the Program in Bioinformatics and Integrative Biology and neurogenetics research in the Neurology Department. The collaboration between the two labs will lead to many future projects in comparative genomics and its application to human diseases.
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