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Grants 2007

The following grants are listed by the month (most recent first) in which they were published in Focus, the newsletter of UMass Medical School.

Select month here or scroll down:

January February March April May June
July August September October November December

 

 

 

December 2007   (back to top)

Steven B. Bird, MD, assistant professor of emergency medicine: Use of an Organophosphorus (OP) Hydrolase for Acute OP Poisoning, National Institute of Environmental Health Sciences, one year, $234,063; recommended for one more year, $203,125.

Alexei Bogdanov, PhD, professor of radiology: MR Signal Amplification for Receptor Imaging, National Institute of Biomedical Imaging and Bioengineering, one year, $360,985; recommended for three more years, $1 million.

Maryann Davis, PhD, assistant professor of psychiatry: Adaptation of Multisystemic Therapy for Transition Age Youth, National Institute of Mental Health, one year, $250,673; recommended for two more years, $469,416.

Chyke A. Doubeni, MD, MPH, assistant professor of family medicine & community health: Understanding Racial and Ethnic Differences in Survival from Colorectal Cancer, National Cancer Institute, one year, $141,539; recommended for four more years, $566,156.

Gerald S. Gleich, MD, assistant professor of family medicine & community health: Practice Improvement in the Treatment of Chronic Pain Through Team and Systems-Based Care, Department of Health and Human Services Residency Training in Primary Care, Health Resources and Services Administration, one year, $120,115; recommended for two more years, $191,408.

Jean A. King, PhD, associate professor of psychiatry: Imaging Nicotine-induced Behavioral Sensitization with fMRI, National Institute on Drug Abuse, one year, $317,500; recommended for four more years, $1.3 million.

Paul Mak, PhD, research assistant professor of surgery: Phytoestrogens and Prostate Cancer Prevention, National Cancer Institute, one year, $81,250; recommended for one more year, $81,250.

William J. McIlvane, PhD, professor of psychiatry: Stimulus Control in Mental Retardation, National Institute of Child Health and Human Development, one year, $724,999; recommended for four more years, $2.9 million.

Gerald A. Schwarting, PhD, professor of cell biology: Migration of Early Olfactory Neuronal Progenitors, National Institute on Deafness and Other Communication Disorders, one year, $333,901; recommended for two more years, $666,385.

Neal Silverman, PhD, associate professor of medicine: Inhibiting the Inhibitor: Small Molecule Screening with Small Pox N1L, National Institute of Allergy and Infectious Diseases; one year, $203,125; recommended for one more year, $243,750.

Gary S. Stein, PhD, the Gerald L. Haidak, MD, and Zelda S. Haidak Professor of Cell Biology and professor and chair of cell biology: Program Project Grant: Bone Cell Structure and Gene Expression, National Institute of Arthritis and Musculoskeletal and Skin Diseases, one year, $1.4 million; recommended for four more years, $5.6 million.

Gyongyi Szabo, MD, PhD, professor of medicine: Ethanols Role in Mediation of Monocyte Suppression, National Institute on Alcohol Abuse and Alcoholism, one year, $48,750; recommended for two more years, $97,500.

William E. Theurkauf, PhD, professor of molecular medicine: Mitotic Response to DNA Damage, National Institute of General Medical Sciences, one year, $46,389; recommended for two more years, $231,316.

Heidi A. Tissenbaum, PhD, associate professor of molecular medicine and a member of the Program in Gene Function and Expression: Glenn Award for Research in Biological Mechanisms of Aging, Glenn Foundation for Medical Research, one year, $50,000.

Robert T. Woodland, PhD, associate professor of molecular genetics & microbiology: Immunodeficiencies That Impair Lymphocyte Survival, National Institute of Allergy and Infectious Diseases; one year, $162,500.

 

November 2007   (back to top)

Robert A. Baldor, MD, professor of family medicine & community health: Predoctoral Training in Primary Care, Department of Health and Human Services, Health Resources and Services Administration, one year, $189,647; recommended for two more years, $337,101.

Roger J. Davis, PhD, the H. Arthur Smith Chair in Cancer Research, Howard Hughes Medical Institute Investigator and professor of molecular medicine and biochemistry & molecular pharmacology: Functional Analysis of JNK in Beta Cells, American Diabetes Association, two years, $90,000.

Dale L. Greiner, PhD, professor of medicine: Diabetogenic Function of Autoimmune Donor Splenocytes, Juvenile Diabetes Research Foundation International, three years, $330,000.

Charles D. Hamad, PhD, associate professor of pediatrics: University Center for Excellence in Developmental Disabilities, Department of Health and Human Services Administration for Children and Families, one year, $490,000; recommended for four more years, $2 million.

Lawrence J. Hayward, MD, PhD, associate professor of neurology and physiology, and Ashutosh Tiwari, PhD, research assistant professor of neurology: Mapping the Aberrant Hydrophobicity of Misfolded SOD1 Mutants that Cause ALS, ALS Therapy Alliance, one year, $77,996.

Anthony N. Imbalzano, PhD, associate professor of cell biology: Spatial Changes in Gene Organization During Adipogenesis, National Institute of Diabetes and Digestive and Kidney Diseases, one year, $203,125; recommended for one more year, $243,750.

Paul Kaufman, PhD, associate professor of molecular medicine: Chromatin Proteins that Ensure DNA Replication Fork Stability, National Science Foundation, $130,000; recommended for two more years, $269,000.

C. Robert Matthews, PhD, the Arthur F. and Helen P. Koskinas Professor and chair of biochemistry & molecular pharmacology, and Osman Bilsel, PhD, research assistant professor of biochemistry & molecular pharmacology: Folding Mechanisms of Dihydrofolate Reductase and the Response Regulators, National Science Foundation, two years, $380,000; recommended for one year, $170,000.

Bharath Nath, AB, an MD/PhD student, in the lab of Gyongyi Szabo, MD, PhD, professor of medicine: HIF Dependent Pathways and Acetylation Events in Alcohol Mediated Liver Injury, Ruth L. Kirschstein National Research Service Award, National Institute on Alcohol Abuse and Alcoholism, one year, $28,637; recommended for three more years, $95,052.

Joel D. Richter, PhD, professor of molecular medicine: Translational Control in Early Mammalian Development, National Institute of Child Health and Human Development, one year, $384,236; recommended for four more years, $1.4 million.

Michael J. Sanderson, PhD, professor of physiology: Airway Hyper-responsiveness: From Molecule to Organ, National Heart, Lung and Blood Institute, one year, $228,571; recommended for two more years, $473,799.

Raymond M. Welsh, PhD, professor of pathology and molecular genetics & microbiology: B Cell Activation During Viral Infection, National Institute of Allergy and Infectious Diseases, one year, $406,250; recommended for four more years, $1.6 million.

Zuoshang Xu, MD, PhD, professor of biochemistry & molecular pharmacology and cell biology: Transgenic Models of ALS Caused by VAPB Mutation, Muscular Dystrophy Association, Inc., one year, $95,000; recommended for one more year, $95,000.

ALS Modeling Based on ANG Deficiency, The Amyotrophic Lateral Sclerosis Association, two years, $159,854.


October 2007   (back to top)

Athena Andreadis, PhD, associate professor of cell biology: Tau Missplicing Caused by RNA Processing Proteins Located on Chromosome 21, National Institute of Child Health and Human Development, one year, $180,922; recommended for one more year, $202,479.

Function of Saitohin, a Novel Protein that Confers Susceptibility to Dementia, National Institute on Aging, one year, $184,875; recommended for one more year, $154,063.

James F. Carey, PhD, a post-doctoral fellow in the lab of Kirsten A. Hagstrom, PhD, assistant professor of molecular medicine: Role of Condensin in Gene Regulation and Heterochromatin Assembly in C. elegans, National Cancer Institute, one year, $49,646; recommended for two more years, $104,176.

Terry S. Field, DSc, associate professor of medicine: Proactive Risk Reduction in Medication Prescribing in the Ambulatory Setting, Agency for Healthcare Research and Quality, one year, $199,975.

Robert J. Goldberg, PhD, professor of medicine: Observational Study of Delay in Heart Failure, National Heart, Lung and Blood Institute, one year, $750,551; recommended for four more years, $2.7 million.

Douglas T. Golenbock, MD, professor of medicine and molecular genetics & microbiology: Group B. Streptococci and Toll-like Receptors, National Institute of Allergy and Infectious Diseases, one year, $187,181.

Matthew J. Gounis, PhD, assistant professor of radiology: Mechanical Clot Obliteration for the Treatment of Stroke, National Institute of Biomedical Imaging and Bioengineering, $383,750; recommended for two more years, $812,500.

Dannel McCollum, PhD, associate professor of molecular genetics & microbiology: Regulation and Function of the Clp 1p Protein Phosphatase, National Institute of General Medical Sciences, one year, $323,216; recommended for three more years, $922,773.

Regulation of Cytokinesis in Fission Yeast, National Institute of General Medical Sciences, one year, $361,599; recommended for three more years, $1.1 million.

Charles G. Sagerström, PhD, associate professor of biochemistry & molecular pharmacology: Role of Nlz Proteins in Hindbrain Development, March of Dimes, three years, $267,239.

Gerald A. Schwarting, PhD, professor of cell biology: Migration of Early Olfactory Neuronal Progenitors, National Institute of Deafness and Other Communication Disorders, one year, $333,901; recommended for two more years, $666,385.

Greenfield Sluder, PhD, professor of cell biology: Centrosome Reduplication and Consequences of Cleavage Failure/Prolonged Mitosis, National Institute of General Medical Sciences, one year, $448,875; recommended for three more years, $1.4 million.

Lawrence J. Stern, PhD, professor of pathology and biochemistry & molecular pharmacology: Interaction of HIV Nef With Its Receptor Binding Partners, National Institute of Allergy and Infectious Diseases, one year, $227,500; recommended for four more years, $1.4 million.

Mario Stevenson, PhD, the David J. Freelander Professor of AIDS Research and professor of molecular medicine and molecular genetics & microbiology: UMass Center for AIDS Research, National Institute of Allergy and Infectious Diseases, one year, $1.3 million; recommended for four more years, $5.4 million.

George B. Witman, PhD, the George F. Booth Chair in the Basic Sciences and professor of cell biology: Flagellar Motility and Assembly, National Institute of General Medical Sciences, one year, $559,746; recommended for four more years, $2.3 million.

September 2007   (back to top)

Silvia Corvera, MD, professor of molecular medicine and cell biology: PI-3 Kinase Effectors in Insulin-Responsive Systems, National Institute of Diabetes and Digestive and Kidney Diseases, one year, $299,813; recommended for three more years, $899,439.

James G. Dobson, PhD, professor of physiology and medicine: Myocardial Adenosine Receptors, National Heart, Lung and Blood Institute, one year, $406,250; recommended for three more years, $1.2 million.

John P. Gusha, DMD, instructor in family medicine & community health: Central Massachusetts Oral Health Initiative, Robert Wood Johnson Community Health Leadership Program, three years, $120,000.

Donald J. Hnatowich, PhD, professor of radiology: PET/SPECT/CT Camera for Research Imaging at UMMS, National Center for Research Resources, one year, $870,000.

Sougata Karmakar, PhD, post-doctoral fellow in the lab of Ellen M. Gravallese, MD, professor of medicine: The Role of BMP3 in the Pathogenesis of Focal Articular Bone Loss in Inflammatory Arthritis, Arthritis National Research Foundation, one year, $50,000.

Timothy F. Kowalik, PhD, associate professor of molecular genetics & microbiology: Cytomegalovirus and Nuclear Tumor Suppressors, National Institute of Allergy and Infectious Diseases, one year, $390,625; recommended for four more years, $1.6 million.

Sarah E. Mortimer, PhD, post-doctoral fellow in the lab of Lawrence J. Stern, PhD, professor of pathology and biochemistry & molecular pharmacology: Kinetic and Structural Investigation of the Mechanism of Action of HLA-DO, National Institute of Allergy and Infectious Diseases, one year, $46,826.

Shimul A. Shah, MD, assistant professor of surgery: Signaling Mechanisms of Hepatitis C-induced Hepatocellular Carcinoma Before and After Transplantation, American Society of Transplant Surgeons—2006 ASTS-Astollas Faculty Development Award, two years, $70,000.

Neal Silverman, PhD, associate professor of medicine: Intracellular innate immune recognition in Drosophila, Burroughs Wellcome Fund—2007 Investigators in Pathogenesis of Infectious Disease Award, five years, $500,000.

Kathleen Walsh, MD, assistant professor of pediatrics: Studying Outpatient Medication Errors in Children with Chronic Conditions, Robert Wood Johnson Foundation Physician Faculty Scholar, three years, $299,957.

 

August 2007   (back to top)

Donna M. Ambrosino, MD, professor of pediatrics: Monoclonal Antibody Development and Manufacturing for the Treatment of Emerging Infections, USA Med Research ACQ Activity, one year, $888,000.

Elliot J. Androphy, MD, the Barbara and Nathan Greenberg Chair in Biomedical Research and professor of medicine and molecular genetics & microbiology: Control of Papillomavirus Expression and Transformation, National Cancer Institute, one year, $360,126; recommended for four more years, $1.4 million.

Anthony Carruthers, PhD, professor of biochemistry & molecular pharmacology and physiology and dean of the Graduate School of Biomedical Sciences: Metabolic Control of Sugar Transport, National Institute of Diabetes and Digestive and Kidney Diseases, one year, $266,332.

Paul R. Clapham, PhD, associate professor of molecular genetics & microbiology and molecular medicine: HIV-1 Tropism Neuropathogenesis and Therapy, National Institute of Mental Health, one year, $406,250; recommended for four more years, $1.5 million.

Michael P. Czech, PhD, professor and chair of molecular medicine and professor of biochemistry & molecular pharmacology: Membrane Topography of Cell Signaling Complexes, National Institute of Diabetes and Digestive and Kidney Diseases, one year, $1.7 million; recommended for four more years, $6.9 million.

J. Lee Hargraves, PhD, research associate professor of family medicine & community health: Perceived Bias in Medical Care Among Ethnically Diverse Adults with Diabetes, National Cancer Institute, one year, $162,500; recommended for one more year, $195,000.

Donald J. Hnatowich, PhD, professor of radiology: Optical Antisense Breast Tumor Targeting, National Cancer Institute, one year, $162,500; recommended for one more year, $195,000.

Jinhee Lee, PhD, DVM, instructor in medicine: Liposome-Based Tuberculosis Vaccine Enhanced by Immunostimulatory Ligands, American Thoracic Society, two years, $100,000.

Mary A. Logan, PhD, post-doctoral fellow in the lab of Marc R. Freeman, PhD, assistant professor of neurobiology: Exploring the Mechanisms of Glial Migration and Glial Responses to Injury, American Cancer Society New England Division Postdoctoral Fellowship, one year, $44,000; recommended for two more years, $94,000.

Nathan A. Marengi, School of Medicine ’08, in the lab of Babs R. Soller, PhD, professor of anesthesiology and surgery: Evaluation of a Low Profile Metabolic Sensor for EVA Studies, Foundation for Anesthesia Education and Research, eight weeks, $3,200.

Arthur M. Mercurio, PhD, professor of cancer biology: Glyolysis, IRS-2 and Metastatic Breast Cancer, Susan G. Komen for the Cure, two years, $300,000.

Matthew J. Paul, PhD, post-doctoral fellow in the lab of William Schwartz, MD, professor of neurology: The Chronobiology of Cohabilitation, National Institute of Neurological Disorders and Stroke, one year, $49,646, recommended for one more year, $51,278.

Nicholas R. Rhind, PhD, assistant professor of biochemistry & molecular pharmacology and cell biology: Single Molecule Analysis of the Regulation of DNA Replication Origin Firing, American Cancer Society, one year, $180,000; recommended for three more years, $540,000.

Joel D. Richter, PhD, professor of molecular medicine: RNA Localization 2006, National Institute of Mental Health, one year, $15,000.

Sean Ryder, PhD, assistant professor of biochemistry & molecular pharmacology: Regulation of Alternative Splicing in Oligodendrocytes by QKI, National Multiple Sclerosis Society, one year, $44,000.

Yong-Xu Wang, PhD, assistant professor of molecular medicine: PPARdelta and Its Co-Regulators in Energy Metabolism, National Institute of Diabetes and Digestive and Kidney Diseases, one year, $203,125.


July 2007   (back to top)

Michael P. Czech, PhD, professor and chair of molecular medicine and professor of biochemistry & molecular pharmacology: Insulin Signaling and Metabolic Regulation in Adipocytes, National Institute of Diabetes and Digestive and Kidney Diseases, one year, $463,351; recommended for four more years, $2.1 million.

Chad E. Darling, MD, assistant professor of emergency medicine: Platelet Reactivity in Acute Chest Pain: Implications for Risk Stratification, Society for Academic Emergency Medicine, one year, $75,000; recommended for one more year, $75,000.

Shannon L. Gibson, PhD, post-doctoral fellow in the lab of Leslie M. Shaw, PhD, assistant professor of cancer biology: IRS-1 Inactivation in Breast Cancer Metastasis, American Cancer Society, New England Division—Virginia Cochary Award for Excellence in Breast Cancer Research Postdoctoral Fellowship, one year, $44,000; recommended for two more years, $94,000.

Michael R. Green, MD, PhD, Howard Hughes Medical Institute Investigator, the Lambi and Sarah Adams Chair in Genetic Research, and professor of molecular medicine, biochemistry & molecular pharmacology and surgery: A Genomewide RNA Interference Screen in Human Mammary Epithelial Cells to Identify Genes Involved in Anoikis, USA Med Research ACQ Activity, three years, $487,500.

Paul Kaufman, PhD, associate professor of molecular medicine: DNA Replication Linked Chromatin Assembly in Yeast, National Institute of General Medical Sciences, one year, $366,850; recommended for three more years, $1.1 million.

David G. Lambright, PhD, professor of molecular medicine and biochemistry & molecular pharmacology: Structural Basis for Rab GTPase Regulated Membrane Trafficking, National Institute of General Medical Sciences, one year, $221,460; recommended for three more years, $975,000.

Julie C. Liu, PhD, post-doctoral fellow in the labs of Gary S. Stein, PhD, the Gerald L. Haidak, MD, and Zelda S. Haidak Professor of Cell Biology and professor and chair of cell biology, and Jane B. Lian, PhD, professor of cell biology: In Vivo Utilization of Runx2 Isoforms During Skeletal Development, National Institute of Arthritis and Musculoskeletal and Skin Diseases, one year, $44,846; recommended for one more year, $46,826.

William L. Marshall, MD, associate professor of medicine: Mechanisms of Vaccinia Virus Innate Immune Inhibition, National Institute of Allergy and Infectious Diseases, one year, $406,250; recommended for four more years, $1.6 million.

Sherry Lynn Pagoto, PhD, assistant professor of medicine: Treating Co-Morbid Obesity and Major Depressive Disorder, National Institute of Mental Health, one year, $500,030; recommended for four more years, $2.1 million.

Karin Przyklenk, PhD, professor of emergency medicine and anesthesiology: Preconditioning Improves Coronary Patency, National Heart, Lung and Blood Institute, one year, $393,750.

Ann R. Rittenhouse, PhD, associate professor of physiology: Role of Arachidonic Isoforms in Nerve Cell Function, National Institute of Neurological Disorders and Stroke, one year, $213,281; recommended for one more year, $177,734.

Charles G. Sagerström, PhD, associate professor of biochemistry & molecular pharmacology: Molecular Analysis of Hindbrain Formation, National Institute of Neurological Disorders and Stroke, one year, $400,000.

Karl Simin, PhD, assistant professor of cancer biology: Improving Methods of Breast Cancer Diagnosis and Treatment, Simeon J. Fortin Charitable Foundation, $50,000; recommended for two more years, $100,000.

 

June 2007   (back to top)

Job Dekker, PhD, assistant professor of biochemistry & molecular pharmacology: Structural Annotation of the Human Genome, National Human Genome Research Institute, one year, $582,000; recommended for two more years, $1.1 million.

Curtis K. Deutsch, PhD, lecturer in psychiatry: Craniofacial Research Program, The Simons Foundation, one year, $119,996.

Thomas J. FitzGerald, MD, professor and chair of radiology oncology and professor of radiology, obstetrics & gynecology and pediatrics: Quality Assurance Review Center, National Cancer Institute, one year, $1.4 million; recommended for four more years, $6 million.

Michael R. Green, MD, PhD, Howard Hughes Medical Institute Investigator, the Lambi and Sarah Adams Chair in Genetic Research, and professor of molecular medicine, biochemistry & molecular pharmacology and surgery: Analysis of the Role of the 24p3/24p3R Proapoptotic Pathway in BCR/ABL-Induced Myeloproliferative Disease Using a Murine Model of Chronic Myelogenous Leukemia, USA Med Research ACQ Activity, 19 months, $162,500.

Donald J. Hnatowich, PhD, professor of radiology: Improved Tumor Radiotherapy by MORF Pretargeting, National Cancer Institute, one year, $240,825; recommended for four more years, $963,300.

Y. Tony Ip, PhD, associate professor of molecular medicine, biochemistry & molecular pharmacology and cell biology: Host-Microbe Interaction in Drosophila Gut, National Institute of Diabetes and Digestive and Kidney Diseases, one year, $203,125; recommended for one more year, $243,750.

Sandra H. Mayrand, MBA, director of the UMMS Regional Science Resource Center: Intel Math Initiative Pilot Program, Intel Foundation, one year, $95,000.

William J. McIlvane, PhD, professor of psychiatry: Optimizing Discrete-Trial Procedures for ASD Children, National Institute of Child Health and Human Development, one year, $217,500; recommended for one more year, $181,250.

Joel D. Richter, PhD, professor of molecular medicine: CPEB and Cell Senescence, National Institute on Aging, one year, $333,125; recommended for four more years, $1.3 million.

Mary Rusckowski, PhD, research associate professor of radiology: Bacterial Specific Oligomers for Infection Detection Through Imaging, National Institute of Allergy and Infectious Diseases, one year, $234,375; recommended for one more year, $203,125.

Christopher M. Sassetti, PhD, assistant professor of molecular genetics & microbiology: Targets for Short-Course TB Therapy, National Institute of Allergy and Infectious Diseases, one year, $203,125; recommended for one more year, $243,750.

Eva Szomolanyi-Tsuda, MD, research assistant professor of pathology: Polyomavirus Infection in Immunodeficient Mice, National Cancer Institute, one year, $261,056; recommended for four more years, $1.04 million.

Mario Stevenson, PhD, the David J. Freelander Professor of AIDS Research and professor of molecular medicine and molecular genetics & microbiology: Preclinical Development of HIV-1 Vif Antagonists, National Institute of Mental Health, one year, $1.2 million; recommended for four more years, $4.6 million.

Cellular Co-Factors of HIV-1 Infection, National Institute of Allergy and Infectious Diseases, one year, $365,625; recommended for four more years, $1.5 million.

Zuoshang Xu, MD, PhD, professor of biochemistry & molecular pharmacology and cell biology: Silencing Mutant SOD1 in Vivo for Treatment of ALS, National Institute of Neurological Disorders and Stroke, one year, $228,164; recommended for one more year, $178,403.

 

May 2007   (back to top)

Lucio H. Castilla, PhD, assistant professor of biochemistry & molecular pharmacology and molecular medicine: Cooperating Genes in INV (16) Acute Myeloid Leukemia, National Cancer Institute, one year, $331,906; recommended for four more years, $1.3 million.

Reid Gilmore, PhD, professor of biochemistry & molecular pharmacology: Assembly and Transfer of N-Linked Oligosaccharides, National Institute of General Medical Sciences, one year, $360,750; recommended for three more years, $1.1 million.

Ronald M. Iorio, PhD, associate professor of molecular genetics & microbiology: Glycoprotein Interactions in Paramyxovirus Fusion, National Institute of Allergy and Infectious Diseases, one year, $213,166; recommended for four more years, $1.3 million.

Adrianne L. Kolpak, GSBS student in the lab of Zheng Z. Bao, PhD, assistant professor of medicine and cell biology: Mechanism of Sonic Hedgehog-Induced Axon Growth and Guidance, National Institute of Neurological Disorders and Stroke, one year, $27,155; recommended for two more years, $54,310.

Craig C. Mello, PhD, Howard Hughes Medical Institute Investigator, Blais University Chair in Molecular Medicine, and professor of molecular medicine and cell biology: RNA Mediated Genetic Interference in C. elegans, National Institutes of General Medical Sciences, one year, $333,125; recommended for three more years, $999,375.

Robert Phillips, MD, PhD, professor of medicine, African American Study of Kidney Disease and Hypertension Cohort Study, National Institute of Diabetes and Digestive and Kidney Diseases, one year, $1.5 million, recommended for four more years, $5 million.

Jitesh Pratap, PhD, research assistant professor of cell biology: Role of Runx2 in Lung Cancer Progression, National Cancer Institute, one year, $65,000; recommended for one more year, $65,000.

Karin Przyklenk, PhD, professor of emergency medicine and anesthesiology: Aging, Adenosine and Platelet-Mediated Thrombosis, National Institute on Aging, one year, $192,188; recommended for one more year, $166,563.

Christopher M. Sassetti, PhD, assistant professor of molecular genetics & microbiology: Mce Transport Systems of Mycobacterium Tuberculosis, National Institute of Allergy and Infectious Diseases, one year, $360,000; recommended for four more years, $1.5 million.

Carole C. Upshur, EdD, professor of family medicine & community health: Addressing Behavior Problems in Preschool Settings, National Institute of Mental Health, one year, $218,646; recommended for two more years, $402,581.

 

April 2007   (back to top)

Alice F. Bonner, MS, clinical instructor in nursing: Patient Safety Culture and Quality Outcomes in Nursing Homes: Examining the Relationship, American Medical Directors Association Foundation, one year, $11,590.

Lucio H. Castilla, PhD, assistant professor of biochemistry & molecular pharmacology and molecular medicine: Mechanisms of Cbfb-MYH11 Mediated Acute Myeloid Leukemia, The Leukemia and Lymphoma Society, one year, $110,000; recommended for four more years, $440,000.

Roger W. Craig, PhD, professor of cell biology: Scanning Electron Microscope for Core EM Facility, National Center for Research Resources, one year, $498,166.

Anthony N. Imbalzano, PhD, associate professor of cell biology: Transcription Factor Function in Chromatin, National Institute of General Medical Sciences, one year, $364,800; recommended for three more years, $1.1 million.

Rebecca Moles, MD, assistant professor of pediatrics: Child Protection Program/Children's Justice Center, Massachusetts Children’s Alliance, one year, $50,000.

Katherine F. Ruiz de Luzuriaga, MD, professor of pediatrics and medicine: Western New England Maternal Pediatric Adolescent AIDS Clinical Trials Unit, National Institute of Allergy and Infectious Diseases, one year, $886,491; recommended for six more years, $3.3 million.

Christopher M. Sassetti, PhD, assistant professor of molecular genetics & microbiology: Virulence Gene Regulation in Mycobacterium Tuberculosis, Charles H. Hood Foundation, Inc., one year, $75,000; recommended for one more year, $75,000.

Eric G. Smith, MD, assistant professor of psychiatry: Risk of Completed Suicide Among Individuals Receiving Anti-epileptics Compared to Individuals Receiving Lithium, American Foundation for Suicide Prevention, one year, $20,000.

Phillip D. Zamore, PhD, the Gretchen Stone Cook Chair in Biomedical Sciences and professor of biochemistry & molecular pharmacology: Understanding microRNA Biogenesis and Function, National Institute of General Medical Sciences, one year, $462,028; recommended for three more years, $1.3 million.

Jianhua Zhou, PhD, assistant professor of medicine: Distal Cis-Elements and Compounds that Regulate Tau Splicing, Institute for the Study of Aging, one year, $50,000.
 

March 2007   (back to top)

Julia D. Andrieni, MD, assistant professor of medicine: Improving Quality of Care for Elderly Patients in the Educational Setting, Josiah Macy, Jr. and the American Board of Internal Medicine Foundations, 18 months, $14,500.

Francis K. Chan, PhD, assistant professor of pathology: Regulation of TRAIL-Induces Apoptosis, National Cancer Institute, one year, $230,750; recommended for three more years, $692,250.

Marianne E. Felice, MD, professor and chair of pediatrics and professor of obstetrics & gynecology: Worcester Infant Mortality Assessment Project, Blue Cross Blue Shield of Massachusetts Foundation, 1 year, $50,000.

Laxman D. Gangwani, PhD, research assistant professor of molecular medicine: Function of the Zinc Finger Protein ZPR1 in Spinal Muscular Atrophy, Muscular Dystrophy Association, Inc., 1 year, $138,842; recommended for two more years, $276,380.

Rachel M. Gerstein, PhD, associate professor of molecular genetics & microbiology: Regulation of V(D)J Recombination in B Cell Development, National Institute of Allergy and Infectious Diseases, 1 year, $346,875; recommended for four more years, $1.3 million.

Elizabeth M. Hearn, PhD, post-doctoral fellow in the lab of Lambertus van den Berg, PhD, assistant professor of molecular medicine: Transport of Hydrophobic Xenobiotics by Gram-Negative Bacterial Membrane Proteins, National Institute of General Medical Sciences, 1 year, $46,826; recommended for one more year, $49,646.

John J. Kelly, MD, associate professor of surgery: Surgical Fellowship Funding, Ethicon Endo-Surgery, Inc., 1 year, $75,000.

Roger S. Luckmann, MD, MPH, associate professor of family medicine & community health: Supporting Patient and Provider Management of Chronic Pain with Personal Digital Assistant Applications linked to Personal Health Records, Robert Wood Johnson Foundation, 18 months, $300,000.

Andrzej  Z. Pietrzykowski, MD, PhD, research instructor in psychiatry: miRNA Regulation of Alcohol Actions in Mammalian Brain, Alcoholic Beverage Medical Research Foundation, 1 year, $50,000; recommended for one more year, $50,000.

Peter M. Pryciak, PhD, associate professor of molecular genetics & microbiology: Yeast Pheromone Signal Transduction, National Institute of General Medical Sciences, one year, $335,676; recommended for three more years, $996,700.

Zuoshang Xu, MD, PhD, associate professor of biochemistry & molecular pharmacology and cell biology: Reverse Genetics Using RNAi, National Institute on Aging, 1 year, $166,563; recommended for one more year, $199,875.

Jianhua Zhou, PhD, assistant professor of medicine: Protecting Against SMN Defects by Stress Response Proteins and Biological Molecules, Muscular Dystrophy Association, Inc., 1 year, $76,722; recommended for two more years, $163,716.

 

February 2007   (back to top)

Elliot J. Androphy, MD, the Barbara and Nathan Greenberg Chair in Biomedical Research and professor of medicine and molecular genetics & microbiology: Novel SMN Interacting Proteins—Novel Targets for Treatment of SMA, Andrew’s Buddies Corporation, one year, $50,000.

Doreen B. Brettler, MD, professor of medicine: Prevention of the Complications of Bleeding Disorders, Centers for Disease Control and Prevention, one year, $379,257; recommended for four more years, $1.52 million.

Timothy Fitzpatrick, associate vice chancellor for master space planning: Nuclear Resonance Mass Spectrometer at the University of Massachusetts Medical School, U.S. Department of Energy, one year, $724,000.

Warren J. Ferguson, MD, associate professor of family medicine & community health: Speaking Together: National Language Services Network, Robert Wood Johnson Foundation, 16 months, $59,992.

Elaine Gabovitch, coordinator of the E.K. Shriver Center’s Leadership Education in Neurodevelopmental and Related Disabilities Program: A Study of Mother’s Perceptions of Family-Centered Care for Children with Autism Spectrum Disorders, Organization for Autism Research, one year, $1,000.

Dale L. Greiner, PhD, professor of medicine: Pilot Studies of Cultured Cord Blood Stem Cells and USSC in vivo, ViaCell, Inc., one year, $7,490.

Jerry H. Gurwitz, MD, the Dr. John Meyers Professor of Primary Care Medicine and professor of medicine and family medicine & community health: Enhancing the Safety of Warfarin in the Nursing Home, Department of Health and Human Services, Agency for Healthcare Research and Quality, one year, $299,997; recommended for two more years, $599,934.

Charlotte Harwood, MD/PhD candidate in the lab of Arthur M. Mercurio, PhD, professor of cancer biology: FLT-1 Function and Signaling in Breast Cancer, USA Med Research ACQ Activity, one year, $32,400; recommended for two more years, $64,800.

Jean A. King, PhD, associate professor of psychiatry, and Joseph DiFranza, MD, professor of family medicine & community health: Effect of Nicotine and Varenicline on Brain Activity in Conscious Rats Using fMRI/BOLD, Pfizer, Inc., one year, $150,000.

Aldo A. Rossini, MD, the William and Doris Krupp Professor of Medicine and professor of medicine and molecular medicine: Using Hematopoietic Stem Cells from Genetically Susceptible Patients to Recapitulate Autoimmune Diabetes, American Diabetes Association, one year, $45,000; recommended for three more years, $135,000.

Gary S. Stein, PhD, the Gerald L. Haidak, MD, and Zelda S. Haidak Professor of Cell Biology and professor and chair of cell biology; Jane B. Lian, PhD, professor of cell biology; and colleague Zvi Bar-Shavit of Hebrew University in Jerusalem, Israel: Runx Control of Osteoclasts, United States-Israel Binational Science Foundation, one year, $48,000.

Janet L. Stein, PhD, professor of cell biology: Runx1 Binding Sites as Scaffolds That Mediate Chromosome Translocation, Fogarty International Center, one year, $39,372; recommended for two more years, $78,744.

John L. Sullivan, MD, professor of pediatrics, molecular medicine, molecular genetics & microbiology and pathology: UMMS Clinical and Translational Science, National Center for Research Resources, one year, $242,472.

Yong-Xu Wang, PhD, assistant professor of molecular medicine: Transcriptional Control of Hepatic Gluconeogenesis by Twist-1, Richard and Susan Smith Family Foundation, one year, $100,000; recommended for one more year, $100,000.

 

January 2007   (back to top)

Edward W. Boyer, MD, PhD, associate professor of emergency medicine: Opioids, Internet Pharmacies, Self-Treated Chronic Pain and HIV, National Institute on Drug Abuse, one year, $283,468; recommended for one more year, $154,153.

Francis K. Chan, PhD, assistant professor of pathology: Regulation of TRAIL-Induces Apoptosis, National Cancer Institute, one year, $230,750; recommended for two more years, $461,500.

Ricardo Gazzinelli, DSc, DVM, professor of medicine: Innate Immune Receptors for Toxoplasma Gondii, National Institute of Allergy and Infectious Diseases, one year, $467,997; recommended for four more years, $2.32 million.

Dhivya Kannabiran, a second-year medical student advised by Michael A. Godkin, PhD, professor of family medicine & community health and medicine: The Effects of Gluten-Free Casein-Free Diets in Behavior of Autistic Children, Special Olympics, U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, one year, $3,500.

Marie A. King, a PhD/MD candidate in the lab of Aldo A. Rossini, MD, the William and Doris Krupp Professor of Medicine and professor of medicine and molecular medicine: Two-Photon Imaging of the Human Alloimmune Response in Humanized Mice, American Diabetes Association Physician Scientist Training Award, one year, $30,000; recommended for two more years, $60,000.

Hardy Kornfeld, MD, professor of medicine: Antimycobacterial Mechanisms of Apoptosis in the Lung, National Heart, Lung and Blood Institute, one year, $406,250; recommended for four more years, $1.63 million.

Annie J. Kruger, a PhD/MD candidate in the lab of Aldo A. Rossini, MD, the William and Doris Krupp Professor of Medicine and professor of medicine and molecular medicine: In Silico Evaluation of Type 1 Diabetes in the BB Rat, American Diabetes Association Physician Scientist Training Award, one year, $30,000; recommended for two more years, $60,000.

Shan Lu, MD, PhD, professor of medicine and biochemistry & molecular pharmacology: Development of Multi-Antigen Subunit SARS Vaccines, National Institute of Allergy and Infectious Diseases, one year, $284,375.

Arthur M. Mercurio, PhD, professor of cancer biology: Mechanisms of Breast Carcinoma Survival, National Cancer Institute, one year, $55,520.

Kevin D. Merdek, post-doctoral fellow in the lab of Arthur M. Mercurio, PhD, professor of cancer biology: Roles of the Alpha6beta4 Integrin in Breast Cancer, National Cancer Institute, one year, $48,796; recommended for two more years, $102,476.

Lori Pbert, PhD, associate professor of medicine: Asthma and Mindfulness-Based Stress Reduction, National Center for Complementary & Alternative Medicine, one year, $324,750; recommended for one more year, $325,000.

Aldo A. Rossini, MD, the William and Doris Krupp Professor of Medicine and professor of medicine and molecular medicine: Adaptive Immunity in Virus-Induced Diabetes in BBDR Rats, National Institute of Allergy and Infectious Diseases, one year, $438,750; recommended for four more years, $1.77 million.

Neal Silverman, PhD, assistant professor of medicine: Activation of Insect Immunity by Gram-Negative Bactria, National Institute of Allergy and Infectious Diseases, one year, $349,344; recommended for five more years, $1.57 million.

Jianhua Zhou, PhD, assistant professor of medicine: Targeting Bcl-x Splicing for Cancer Treatment, National Cancer Institute, one year, $81,250; recommended for one more year, $81,250.


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