2008

NJ Martinez, MC Ow, JS Reece-Hoyes, MI Barrasa, VR Ambros and AJ Walhout (2008) Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity. Genome Res., 18: 2005-2015.

T Kaplan, C-L Liu, JA Erkmann, J Holik, M Grunstein, PD Kaufman, N Friedman and OJ Rando (2008) Cell cycle- and chaperone-mediated regulation of H3K56ac incorporation in yeast. PLoS Genetics, 4: e1000270.

J Dekker Mapping in vivo chromatin interactions in yeast suggests an extended chromatin fiber with regional variation in compaction. J. Biol. Chem., 283: 34532-34540.

LJ Barber, JL Youds, JD Ward, MJ McIlwraith, NJ O'Neil MI Petalcorin, JS Martin, SJ Collis, SB Cantor, M Auclair, HA Tissenbaum, SC West, AM Rose and SJ Boulton (2008) RTEL1 maintains genomic stability by suppressing homologous recombination. Cell, 135: 261-271.

S Gobeil, X Zhu, CJ Doillon and MR Green (2008) A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene. Genes Dev., 22: 2932-2940.

A Miele and J Dekker (2008) Long-range looping interactions and gene regulation. Mol. BioSyst., 4: 1046-1057.

NJ Martinez, MC Ow, MI Barrasa, M Hammell, R Sequerra, L Doucette-Stamm, FP Roth, V Ambros and AJ Walhout (2008) A C. elegans genome-scale microRNA network contains composite feedback loops with high flux capacity. Genes Dev., 22: 2535-2549.

MC Ow, NJ Martinez, PH Olsen, HS Silverman, MI Barrasa, B Conradt, AJ Walhout and V Ambros (2008) The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans. Genes Dev., 22: 2520-2534.

CE Berndsen, T Tsubota, SE Lindner, S Lee, JM Holton, PD Kaufman, JL Keck and JM Denu (2008) Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75. Nat. Struct. Mol. Biol., 15: 948-956.

H Shen, X Zheng, J Shen, L Zhang, R Zhao and MR Green (2008) Distinct activities of the DexD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Genes Dev., 22: 1796-1803.

MB Noyes, RG Christensen, A Wakabayashi, GD Stormo, MH Brodsky and SA Wolfe (2008) Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell, 133: 1277-1289.

M Bhati, C Lee, AL Nancarrow, M Lee, VJ Craig, I Bach, JM Guss, JP Mackay and JM MAtthews (2008) Implementing the LIM code: The structural basis for cell type-specific assembly of LIM-homeodomain complexes. EMBO J., 27: 2018-2029.

X Meng, MB Noyes, LJ Zhu, ND Lawson and SA Wolfe (2008) Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases. Nat. Biotechnol. 26, 695-701.

SC Pino, B O'Sullivan-Murphy, EA Lidstone, TB Thornley, A Jurczyk, F Urano, DL Greiner, JP Mordes, AA Rossini and R Bortell (2008) Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response. Cell Stress Chaperones, epub ahead of print.

YH Kuo, RM Gerstein and LH Castilla (2008) Cbfbeta-SMMHC impairs differentiation of common lymphoid progenitors and reveals an essential role for RUNX in early B-cell development.Blood 111: 1543-1551.

JR Keys, MR Tallack, Y Zhan, P Papathanasiou, CC Goodnow, KM Gaensler, M Crossley, J Dekker and AC Perkins (2008) A mechanism for Ikaros regulation of human globin gene switching. Br. J. Haematol. 141: 398-406.

J Dekker (2008) Gene regulation in the third dimension. Science 319: 1793-1794.

A Mukhopadhyay, B Deplancke, AJ Walhout and HA Tissenbaum (2008) Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans. Nat. Protocol. 3: 698-709.

D Luo, Y He, H Zhang, L Yu, H Chen, Z Xu, S Tang, F Urano and W Min (2008) AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. J. Biol. Chem, epub ahead of print

KL Lipson, R Ghosh and F Urano (2008) The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells. PLoS ONE 3: e1648.

CA Grove and AJM Walhout (2008) Transcription factor functionality and transcription regulatory networks. Mol. Biosys. 4: 309-314.

JP Morton, DS Klimstra, ME Mongeau and BC Lewis (2008) Trp53 deletion stimulates the formation of metastatic pancreatic tumors. Am. J. Pathol. 172: 1081-1087.

N Wajapeyee, RW Serra, X Zhu, M Mahalingam and MR Green (2008) Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 132: 363-374.

JK Acharya, U Dasgupta, SS Rawat, C Yuan, PD Sanxaridis, I Yonamine, P Karim, K Nagashima, MH Brodsky, T Tsunoda and U Acharya. (2008) Cell non-autonomous function of ceramidase in photoreceptor homeostasis. Neuron 57: 69-79.

YW Chen, S Paliwal, K Draheim, SR Grossman and BC Lewis (2008) p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein. Cancer Res. 68: 476-482.

KT Chambers, JA Unverferth, SM Weber, RC Wek, F Urano and JA Corbett (2008) The role of nitric oxide and the unfolded protein response in cytokine induced beta-cell death. Diabetes 57: 124-132.