Instrumentation:

                                MALDI QIT TOF                                              

This unique hybrid MALDI TOF instrument incorporates an ion trap between the source and the reflectron. This geometry decouples the ionization from the time-of-flight measurement which removes variability in mass accuracy which occur when measuring time of flight from the target surface. The ion trap acts as both a precursor selector and collision cell during MS/MS analysis which is facilitated via collisional induced dissociation (CID) using argon as the heavy gas.



John Leszyk on left and Koichi Tanaka, 2002 Nobel Prize winner in
Chemistry and inventor of the Axima QIT instrument on right.
This instrument installed in 2003 is used predominantly to identify
low level 2D gel spots as well as phosphopeptides due to its exceptional
sensitivity and mass accuracy.