Analytical Core

The Analytical Core performs a high-throughput measurement of serum and tissue levels of hormones, metabolites and cytokines that are known to affect metabolism.

  • Measures serum and tissue levels of hormones (insulin, leptin, adiponectin), cytokines (TNF-a, IL-6, IL-1) and chemokines (MCP, MIP, VEGF) using Luminex (photo).
  • Measures serum and tissue levels of metabolites (lipid and hepatic panel) and electrolytes using Cobas Clinical Chemistry Analyzer.
  • Performs standardized biochemical procedures to measure intracellular metabolism in individual organs.
  • Performs complex molecular procedures to assess intracellular signaling pathway associated with insulin, metabolism and inflammation.
DIRECTOR

David M. Harlan, M.D.
William and Doris Krupp Professor of Medicine
Co-Director, Diabetes Center of Excellence
UMass Memorial Medical Center and
Professor of Medicine and Pediatrics
Chief, Division of Diabetes
University of Massachusetts Medical School
508-856-3800 (phone)
David.Harlan@umassmemorial.org

 Harlan 2010
CO-DIRECTOR

Randall Friedline, Ph.D.
Instructor of Molecular Medicine
508-856-8791 (phone)
randall.friedline@umassmed.edu

Randall Friedline

Address:

University of Massachusetts Medical School
368 Plantation Street
The Albert Sherman Center
9th Floor, Room 1015
Worcester, MA 01605

 

 

 Overview Mice2