PMM Graduate Student Publications (2009-2012)

Nechama M, Lin CL, Richter JD. An Unusual Two-Step Control of CPEB Destruction by Pin1. Mol Cell Biol. 2013 Jan;33(1):48-58. doi: 10.1128/MCB.00904-12. Epub 2012 Oct 22. PubMed PMID: 23090969.

Wang M, Amano SU, Roth Flach RJ, Chawla A, Aouadi M, Czech MP. Identification of Map4k4 as a novel suppressor of skeletal muscle differentiation. Mol Cell Biol. 2012 Dec 3. [Epub ahead of print] PubMed PMID: 23207904.

Hung HF, Hehnly H, Doxsey S. Multiplying madly: Deacetylases take charge of centrosome duplication and amplification. Cell Cycle. 2012 Dec 1;11(23):4304. doi: 10.4161/cc.22812. Epub 2012 Nov 16. PubMed PMID: 23159860.

Hung CM, Garcia-Haro L, Sparks CA, Guertin DA. mTOR-Dependent Cell Survival Mechanisms. Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12). doi:pii: a008771. 10.1101/cshperspect.a008771. PubMed PMID: 23124837.

Zhang F, Wang J, Xu J, Zhang Z, Koppetsch BS, Schultz N, Vreven T, Meignin C, Davis I, Zamore PD, Weng Z, Theurkauf WE. UAP56 Couples piRNA Clusters to the Perinuclear Transposon Silencing Machinery. Cell. 2012 Nov 9;151(4):871-84. doi: 10.1016/j.cell.2012.09.040. PubMed PMID: 23141543; PubMed Central PMCID: PMC3499805.

Hehnly H, Chen CT, Powers CM, Liu HL, Doxsey S. The centrosome regulates the rab11- dependent recycling endosome pathway at appendages of the mother centriole. Curr Biol. 2012 Oct 23;22(20):1944-50. doi: 10.1016/j.cub.2012.08.022. Epub 2012 Sep 13. PubMed PMID: 22981775.

Chen CT, Doxsey SJ. An MBoC favorite: role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP. Mol Biol Cell. 2012 Oct;23(19):3775. doi: 10.1091/mbc.E12-03-0186. PubMed PMID: 23024182; PubMed Central PMCID: PMC3459854.

Sanchez-Gurmaches J, Hung CM, Sparks CA, Tang Y, Li H, Guertin DA. PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors. Cell Metab. 2012 Sep 5;16(3):348-62. PubMed PMID: 22940198; PubMed Central PMCID: PMC3488151.

Chen CT, Hehnly H, Doxsey SJ. Orchestrating vesicle transport, ESCRTs and kinase surveillance during abscission. Nat Rev Mol Cell Biol. 2012 Jul 11;13(8):483-8. doi: 10.1038/nrm3395. Review. PubMed PMID: 22781903.

Shirayama M, Seth M, Lee HC, Gu W, Ishidate T, Conte D Jr, Mello CC. piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germline. Cell. 2012 Jul 6;150(1):65-77. doi: 10.1016/j.cell.2012.06.015. Epub 2012 Jun 25. PubMed PMID: 22738726.

Keady BT, Samtani R, Tobita K, Tsuchya M, San Agustin JT, Follit JA, Jonassen JA, Subramanian R, Lo CW, Pazour GJ. IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport. Dev Cell. 2012 May 15;22(5):940-51. doi: 10.1016/j.devcel.2012.04.009. PubMed PMID: 22595669; PubMed Central PMCID: PMC3366633.

Lin CL, Huang YT, Richter JD. Transient CPEB dimerization and translational control. RNA. 2012 May;18(5):1050-61. doi: 10.1261/rna.031682.111. Epub 2012 Mar 28. PubMed PMID: 22456264; PubMed Central PMCID: PMC3334692.

Navaroli DM, Bellvé KD, Standley C, Lifshitz LM, Cardia J, Lambright D, Leonard D, Fogarty KE, Corvera S. Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):E471-80. doi: 10.1073/pnas.1115495109. Epub 2012 Jan 30. PubMed PMID: 22308388; PubMed Central PMCID: PMC3286945.

Cellurale C, Girnius N, Jiang F, Cavanagh-Kyros J, Lu S, Garlick DS, Mercurio AM, Davis RJ. Role of JNK in mammary gland development and breast cancer. Cancer Res. 2012 Jan 15;72(2):472-81. doi: 10.1158/0008-5472.CAN-11-1628. Epub 2011 Nov 29. PubMed PMID: 22127926; PubMed Central PMCID: PMC3261359.

Alexandrov IM, Ivshina M, Jung DY, Friedline R, Ko HJ, Xu M, O'Sullivan-Murphy B, Bortell R, Huang YT, Urano F, Kim JK, Richter JD. Cytoplasmic polyadenylation element binding protein deficiency stimulates PTEN and Stat3 mRNA translation and induces hepatic insulin resistance. PLoS Genet. 2012 Jan;8(1):e1002457. doi: 10.1371/journal.pgen.1002457. Epub 2012 Jan 12. PubMed PMID: 22253608; PubMed Central PMCID: PMC3257279.

Young JL, Mora A, Cerny A, Czech MP, Woda B, Kurt-Jones EA, Finberg RW, Corvera S. CD14 deficiency impacts glucose homeostasis in mice through altered adrenal tone. PLoS One. 2012;7(1):e29688. doi: 10.1371/journal.pone.0029688. Epub 2012 Jan 13. PubMed PMID: 22253759; PubMed Central PMCID: PMC3258240.

 

2011

Khurana JS, Wang J, Xu J, Koppetsch BS, Thomson TC, Nowosielska A, Li C, Zamore PD, Weng Z, Theurkauf WE. Adaptation to P element transposon invasion in Drosophila melanogaster. Cell. 2011 Dec 23;147(7):1551-63. doi: 10.1016/j.cell.2011.11.042. PubMed PMID: 22196730; PubMed Central PMCID: PMC3246748.

Fitzgibbons TP, Kogan S, Aouadi M, Hendricks GM, Straubhaar J, Czech MP. Similarity of mouse perivascular and brown adipose tissues and their resistance to diet-induced inflammation. Am J Physiol Heart Circ Physiol. 2011 Oct;301(4):H1425-37. doi: 10.1152/ajpheart.00376.2011. Epub 2011 Jul 15. PubMed PMID: 21765057; PubMed Central PMCID: PMC3197360.

Navaroli DM, Stevens ZH, Uzelac Z, Gabriel L, King MJ, Lifshitz LM, Sitte HH, Melikian HE. The plasma membrane-associated GTPase Rin interacts with the dopamine transporter and is required for protein kinase C-regulated dopamine transporter trafficking. J Neurosci. 2011 Sep 28;31(39):13758-70. doi: 10.1523/JNEUROSCI.2649-11.2011. PubMed PMID: 21957239; PubMed Central PMCID: PMC3205929.

Kuo TC, Chen CT, Baron D, Onder TT, Loewer S, Almeida S, Weismann CM, Xu P, Houghton JM, Gao FB, Daley GQ, Doxsey S. Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nat Cell Biol. 2011 Sep 11;13(10):1214-23. doi: 10.1038/ncb2332. Erratum in: Nat Cell Biol. 2011 Dec;13(12):1467. PubMed PMID: 21909099.

Tesz GJ, Aouadi M, Prot M, Nicoloro SM, Boutet E, Amano SU, Goller A, Wang M, Guo CA, Salomon WE, Virbasius JV, Baum RA, O'Connor MJ Jr, Soto E, Ostroff GR, Czech MP. Glucan particles for selective delivery of siRNA to phagocytic cells in mice. Biochem J. 2011 Jun 1;436(2):351-62. doi: 10.1042/BJ20110352. PubMed PMID: 21418037.

Burns DM, D'Ambrogio A, Nottrott S, Richter JD. CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation. Nature. 2011 May 5;473(7345):105-8. doi: 10.1038/nature09908. Epub 2011 Apr 10. PubMed PMID: 21478871; PubMed Central PMCID: PMC3088779.

Tabuchi TM, Deplancke B, Osato N, Zhu LJ, Barrasa MI, Harrison MM, Horvitz HR, Walhout AJ, Hagstrom KA. Chromosome-biased binding and gene regulation by the Caenorhabditis elegans DRM complex. PLoS Genet. 2011 May;7(5):e1002074. doi: 10.1371/journal.pgen.1002074. Epub 2011 May 12. PubMed PMID: 21589891; PubMed Central PMCID: PMC3093354.

Narasimhan SD, Yen K, Bansal A, Kwon ES, Padmanabhan S, Tissenbaum HA. PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism. PLoS Genet. 2011 Apr;7(4):e1001377. doi: 10.1371/journal.pgen.1001377. Epub 2011 Apr 21. PubMed PMID: 21533078; PubMed Central PMCID: PMC3080858.

Cellurale C, Sabio G, Kennedy NJ, Das M, Barlow M, Sandy P, Jacks T, Davis RJ. Requirement of c-Jun NH(2)-terminal kinase for Ras-initiated tumor formation. Mol Cell Biol. 2011 Apr;31(7):1565-76. doi: 10.1128/MCB.01122-10. Epub 2011 Jan 31. PubMed PMID: 21282468; PubMed Central PMCID: PMC3135291.

Delaval B, Bright A, Lawson ND, Doxsey S. The cilia protein IFT88 is required for spindle orientation in mitosis. Nat Cell Biol. 2011 Apr;13(4):461-8. doi: 10.1038/ncb2202. Epub 2011 Mar 27. PubMed PMID: 21441926; PubMed Central PMCID: PMC3073523.

Musich T, Peters PJ, Duenas-Decamp MJ, Gonzalez-Perez MP, Robinson J, Zolla-Pazner S, Ball JK, Luzuriaga K, Clapham PR. A conserved determinant in the V1 loop of HIV-1 modulates the V3 loop to prime low CD4 use and macrophage infection. J Virol. 2011 Mar;85(5):2397-405. doi: 10.1128/JVI.02187-10. Epub 2010 Dec 15. PubMed PMID: 21159865; PubMed Central PMCID: PMC3067776.

Yen K, Narasimhan SD, Tissenbaum HA. DAF-16/Forkhead box O transcription factor: many paths to a single Fork(head) in the road. Antioxid Redox Signal. 2011 Feb 15;14(4):623-34. doi: 10.1089/ars.2010.3490. Epub 2010 Nov 30. PubMed PMID: 20673162; PubMed Central PMCID: PMC3021330.

Burkart A, Shi X, Chouinard M, Corvera S. Adenylate kinase 2 links mitochondrial energy metabolism to the induction of the unfolded protein response. J Biol Chem. 2011 Feb 11;286(6):4081-9. doi: 10.1074/jbc.M110.134106. Epub 2010 Sep 27. PubMed PMID: 20876536; PubMed Central PMCID: PMC3039340.


2010

 Ranjit S, Boutet E, Gandhi P, Prot M, Tamori Y, Chawla A, Greenberg AS, Puri V, Czech MP. Regulation of fat specific protein 27 by isoproterenol and TNF-α to control lipolysis in murine adipocytes. J Lipid Res. 2011 Feb;52(2):221-36. doi: 10.1194/jlr.M008771. Epub 2010 Nov 20. PubMed PMID: 21097823; PubMed Central PMCID: PMC3023542.

Khurana JS, Xu J, Weng Z, Theurkauf WE. Distinct functions for the Drosophila piRNA pathway in genome maintenance and telomere protection. PLoS Genet. 2010 Dec 16;6(12):e1001246. doi: 10.1371/journal.pgen.1001246. PubMed PMID: 21179579; PubMed Central PMCID: PMC3003142.

Yen K, Le TT, Bansal A, Narasimhan SD, Cheng JX, Tissenbaum HA. A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods. PLoS One. 2010 Sep 16;5(9). doi:pii: e12810. 10.1371/journal.pone.0012810. PubMed PMID: 20862331; PubMed Central PMCID: PMC2940797.

Cellurale C, Weston CR, Reilly J, Garlick DS, Jerry DJ, Sluss HK, Davis RJ. Role of JNK in a Trp53-dependent mouse model of breast cancer. PLoS One. 2010 Aug 30;5(8):e12469. doi: 10.1371/journal.pone.0012469. PubMed PMID: 20814571; PubMed Central PMCID: PMC2930003.

DiNitto JP, Lee MT, Malaby AW, Lambright DG. Specificity and membrane partitioning of Grsp1 signaling complexes with Grp1 family Arf exchange factors. Biochemistry. 2010 Jul 27;49(29):6083-92. doi: 10.1021/bi1000454. PubMed PMID: 20527794; PubMed Central PMCID: PMC2912425.

Kwon ES, Narasimhan SD, Yen K, Tissenbaum HA. A new DAF-16 isoform regulates longevity. Nature. 2010 Jul 22;466(7305):498-502. doi: 10.1038/nature09184. Epub 2010 Jul 7. PubMed PMID: 20613724; PubMed Central PMCID: PMC3109862.

Duenas-Decamp MJ, Peters PJ, Repik A, Musich T, Gonzalez-Perez MP, Caron C, Brown R, Ball J, Clapham PR. Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis. Future Virol. 2010 Jul;5(4):435-451. PubMed PMID: 20930940; PubMed Central PMCID: PMC2949073.

Arda HE, Taubert S, MacNeil LT, Conine CC, Tsuda B, Van Gilst M, Sequerra R, Doucette-Stamm L, Yamamoto KR, Walhout AJ. Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network. Mol Syst Biol. 2010 May 11;6:367. doi: 10.1038/msb.2010.23. PubMed PMID: 20461074; PubMed Central PMCID: PMC2890327.

Walz HA, Shi X, Chouinard M, Bue CA, Navaroli DM, Hayakawa A, Zhou QL, Nadler J, Leonard DM, Corvera S. Isoform-specific regulation of Akt signaling by the endosomal protein WDFY2. J Biol Chem. 2010 May 7;285(19):14101-8. doi: 10.1074/jbc.M110.110536. Epub 2010 Feb 26. PubMed PMID:

Guntur KV, Guilherme A, Xue L, Chawla A, Czech MP. Map4k4 negatively regulates peroxisome proliferator-activated receptor (PPAR) gamma protein translation by suppressing the mammalian target of rapamycin (mTOR) signaling pathway in cultured adipocytes. J Biol Chem. 2010 Feb 26;285(9):6595-603. doi: 10.1074/jbc.M109.068502. Epub 2009 Dec 28. PubMed PMID: 20038583; PubMed Central PMCID: PMC2825455.

Vasale JJ, Gu W, Thivierge C, Batista PJ, Claycomb JM, Youngman EM, Duchaine TF, Mello CC, Conte D Jr. Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3582-7. doi: 10.1073/pnas.0911908107. Epub 2010 Feb 2. PubMed PMID: 20133583; PubMed Central PMCID: PMC2840456.

Conine CC, Batista PJ, Gu W, Claycomb JM, Chaves DA, Shirayama M, Mello CC. Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3588-93. doi: 10.1073/pnas.0911685107. Epub 2010 Feb 4. PubMed PMID: 20133686; PubMed Central PMCID: PMC2840486.

Navaroli DM, Melikian HE. Insertion of tetracysteine motifs into dopamine transporter extracellular domains. PLoS One. 2010 Feb 9;5(2):e9113. doi: 10.1371/journal.pone.0009113. PubMed PMID: 20161733; PubMed Central PMCID: PMC2817725. 

Lin CL, Evans V, Shen S, Xing Y, Richter JD. The nuclear experience of CPEB: implications for RNA processing and translational control. RNA. 2010 Feb;16(2):338-48. doi: 10.1261/rna.1779810. Epub 2009 Dec 29. PubMed PMID: 20040591; PubMed Central PMCID: PMC2811663.

Follit JA, Li L, Vucica Y, Pazour GJ. The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence. J Cell Biol. 2010 Jan 11;188(1):21-8. doi: 10.1083/jcb.200910096. Epub 2010 Jan 4. PubMed PMID: 20048263; PubMed Central PMCID: PMC2812845.

 

2009

Sinha, M., Watanabe, S., Johnson, A., Moazed, D., and Peterson, C.L. Recombinational repair within heterochromatin requires ATP-dependent chromatin remodeling. Cell 18:1109-1121. 2009 PMCID: PMC2791047 

Arda HE, Walhout AJ. Gene-centered regulatory networks. Brief Funct Genomics. 2010 Jan;9(1):4-12. doi: 10.1093/bfgp/elp049. Epub 2009 Dec 13. Review. PubMed PMID: 20008400; PubMed Central PMCID: PMC3096532.

Oza P, Peterson CL. Opening the DNA repair toolbox: localization of DNA double strand breaks to the nuclear periphery. Cell Cycle. 2010 Jan 1;9(1):43-9. Epub 2010 Jan 13. PubMed PMID: 20016273.


Narasimhan SD, Mukhopadhyay A, Tissenbaum HA. InAKTivation of insulin/IGF-1 signaling by dephosphorylation. Cell Cycle. 2009 Dec;8(23):3878-84. PubMed PMID: 19901535; PubMed Central PMCID: PMC3109867.

Gu W, Shirayama M, Conte D Jr, Vasale J, Batista PJ, Claycomb JM, Moresco JJ, Youngman EM, Keys J, Stoltz MJ, Chen CC, Chaves DA, Duan S, Kasschau KD, Fahlgren N, Yates JR 3rd, Mitani S, Carrington JC, Mello CC. Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline. Mol Cell. 2009 Oct 23;36(2):231-44. doi: 10.1016/j.molcel.2009.09.020. Epub 2009 Oct 1. PubMed PMID: 19800275; PubMed Central PMCID: PMC2776052.

Claycomb JM, Batista PJ, Pang KM, Gu W, Vasale JJ, van Wolfswinkel JC, Chaves DA, Shirayama M, Mitani S, Ketting RF, Conte D Jr, Mello CC. The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell. 2009 Oct 2;139(1):123-34. doi: 10.1016/j.cell.2009.09.014. PubMed PMID: 19804758; PubMed Central PMCID: PMC2766185.

Lee MT, Mishra A, Lambright DG. Structural mechanisms for regulation of membrane traffic by rab GTPases. Traffic. 2009 Oct;10(10):1377-89. doi: 10.1111/j.1600-0854.2009.00942.x. Epub 2009 May 19. Review. PubMed PMID: 19522756.

Klattenhoff C, Xi H, Li C, Lee S, Xu J, Khurana JS, Zhang F, Schultz N, Koppetsch BS, Nowosielska A, Seitz H, Zamore PD, Weng Z, Theurkauf WE. The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters. Cell. 2009 Sep 18;138(6):1137-49. doi: 10.1016/j.cell.2009.07.014. Epub 2009 Sep 3. PubMed PMID: 19732946; PubMed Central PMCID: PMC2770713.

Chatterjee M, Ip YT. Pathogenic stimulation of intestinal stem cell response in Drosophila. J Cell Physiol. 2009 Sep;220(3):664-71. doi: 10.1002/jcp.21808. PubMed PMID: 19452446.

Narasimhan SD, Yen K, Tissenbaum HA. Converging pathways in lifespan regulation. Curr Biol. 2009 Aug 11;19(15):R657-66. doi: 10.1016/j.cub.2009.06.013. Review. PubMed PMID: 19674551; PubMed Central PMCID: PMC3109866.

Follit JA, Xu F, Keady BT, Pazour GJ. Characterization of mouse IFT complex B. Cell Motil Cytoskeleton. 2009 Aug;66(8):457-68. doi: 10.1002/cm.20346. PubMed PMID: 19253336; PubMed Central PMCID: PMC2753169.

Guilherme A, Tesz GJ, Guntur KV, Czech MP. Tumor necrosis factor-alpha induces caspase-mediated cleavage of peroxisome proliferator-activated receptor gamma in adipocytes. J Biol Chem. 2009 Jun 19;284(25):17082-91. doi: 10.1074/jbc.M809042200. Epub 2009 Mar 25. PubMed PMID: 19321447; PubMed Central PMCID: PMC2719346.

Reece-Hoyes JS, Deplancke B, Barrasa MI, Hatzold J, Smit RB, Arda HE, Pope PA, Gaudet J, Conradt B, Walhout AJ. The C. elegans Snail homolog CES-1 can activate gene expression in vivo and share targets with bHLH transcription factors. Nucleic Acids Res. 2009 Jun;37(11):3689-98. doi: 10.1093/nar/gkp232. Epub 2009 Apr 16. PubMed PMID: 19372275; PubMed Central PMCID: PMC2699517.

Aouadi M, Tesz GJ, Nicoloro SM, Wang M, Chouinard M, Soto E, Ostroff GR, Czech MP. Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation. Nature. 2009 Apr 30;458(7242):1180-4. doi: 10.1038/nature07774. PubMed PMID: 19407801; PubMed Central PMCID: PMC2879154.

Oza P, Jaspersen SL, Miele A, Dekker J, Peterson CL. Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery. Genes Dev. 2009 Apr 15;23(8):912-27. doi: 10.1101/gad.1782209. PubMed PMID: 19390086; PubMed Central PMCID: PMC2675867.
Free full textCited in PMCRelated citations

Padmanabhan S, Mukhopadhyay A, Narasimhan SD, Tesz G, Czech MP, Tissenbaum HA. A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation. Cell. 2009 Mar 6;136(5):939-51. doi: 10.1016/j.cell.2009.01.025. Epub 2009 Feb 26. PubMed PMID: 19249087; PubMed Central PMCID: PMC2707143.

Benoit B, He CH, Zhang F, Votruba SM, Tadros W, Westwood JT, Smibert CA, Lipshitz HD, Theurkauf WE. An essential role for the RNA-binding protein Smaug during the Drosophila maternal-to-zygotic transition. Development. 2009 Mar;136(6):923-32. doi: 10.1242/dev.031815. PubMed PMID: 19234062; PubMed Central PMCID: PMC2727558.

Chen CT, Doxsey S. A last-minute rescue of trapped chromatin. Cell. 2009 Feb 6;136(3):397-9. doi: 10.1016/j.cell.2009.01.028. PubMed PMID: 19203574.

SanAgustin JT, Follit JA, Hendricks G, Pazour GJ. Scanning electron microscopy to examine cells and organs. Methods Cell Biol. 2009;91:81-7. doi: 10.1016/S0091-679X(08)91004-9. Epub 2009 Dec 1. PubMed PMID: 20409781.